Rai Raj, Raval Rushik, Khandeparker Rakshit Vijay Sinai, Chidrawar Swati K, Khan Abdul Ahad, Ganpat Makne Sachin
Professor, Department of Oral and Maxillofacial Surgery, DR. G.D. Pols Foundation YMT Dental College and Hospital, Kharghar, Navi Mumbai, Maharashtra, India.
Post Graduate Student, Department of Oral and Maxillofacial Surgery, Maharaja Ganga Singh Dental College and Research Centre, Sriaganganagar, Rajasthan, India.
J Int Oral Health. 2015 Sep;7(9):138-42.
Within the precedent decade, a new field of "tissue engineering" or "tissue regeneration" emerge that offers an innovative and exhilarating substitute for maxillofacial reconstruction. It offers a new option to supplement existing treatment regimens for reconstruction/regeneration of the oral and craniofacial complex, which includes the teeth, periodontium, bones, soft tissues (oral mucosa, conjunctiva, skin), salivary glands, and the temporomandibular joint (bone and cartilage), as well as blood vessels, muscles, tendons, and nerves. Tissue engineering is based on harvesting the stem cells which are having potential to form an organ. Harvested cells are then transferred into scaffolds that are manufactured in a laboratory to resemble the structure of the desired tissue to be replaced. This article reviews the principles of tissue engineering and its various applications in oral and maxillofacial surgery.
在前十年中，一个名为“组织工程”或“组织再生”的新领域出现了，它为颌面重建提供了一种创新且令人振奋的替代方案。它为补充口腔和颅面复合体（包括牙齿、牙周组织、骨骼、软组织（口腔黏膜、结膜、皮肤）、唾液腺以及颞下颌关节（骨骼和软骨））的重建/再生现有治疗方案提供了新选择，还包括血管、肌肉、肌腱和神经。组织工程基于获取具有形成器官潜力的干细胞。然后将获取的细胞转移到在实验室制造的支架中，这些支架类似于要替换的目标组织的结构。本文综述了组织工程的原理及其在口腔颌面外科中的各种应用。
