土耳其东南部青少年特发性关节炎患儿的评估：单中心经验
Evaluation of children with juvenile idiopathic arthritis in southeastern Turkey: a single center experience.
作者信息
Şen V, Ece A, Uluca Ü, Güneş A, Yel S, Tan I, Karabel D, Yıldırım B, Haspolat K
机构信息
Pediatric Department.
Pediatric Rheumatology Department, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
出版信息
Hippokratia. 2015 Jan-Mar;19(1):63-8.
BACKGROUND
The aim of this study was to investigate the disease characteristics of children with juvenile idiopathic arthritis (JIA) in southeast Turkey.
METHODS
The International League of Associations for Rheumatology (ILAR) criteria were used to diagnose JIA. Hospital records of the Pediatric Rheumatology Unit, of the Dicle University Hospital, were reviewed retrospectively and demographic, clinical and laboratory data were recorded.
RESULTS
Totally 213 children (103 boys, 110 girls), with an age range of 1.6-18 years were enrolled. The mean age of the disease onset was 8.1 years. Polyarticular type was the most common (42.3%) presentation. The frequencies of other JIA subtypes were as follows: oligoarticular 37.1%, systemic 8.9%, enthesitis-related arthritis (ERA) 10.8% and psoriatic arthritis 0.9%. The knees (74.2%) and ankles (54.0%) were the most commonly affected joints. Uveitis was found in 4.2% of patients. Anti-nuclear antibodies were positive in 11.7% and HLA-B27 in 2.8% of patients. Active disease was seen in 57 (26.7%) patients at the last visit.
CONCLUSION
In the present study, polyarticular JIA was the predominant subtype and there were fewer patients with positive ANA or uveitis compared to previous studies. Hippokratia 2015, 19 (1): 63-68.
背景
本研究旨在调查土耳其东南部青少年特发性关节炎（JIA）患儿的疾病特征。
方法
采用国际风湿病联盟（ILAR）标准诊断JIA。回顾性分析了狄克莱大学医院儿科风湿病科的医院记录，并记录了人口统计学、临床和实验室数据。
结果
共纳入213例年龄在1.6 - 18岁之间的儿童（103例男孩，110例女孩）。疾病发病的平均年龄为8.1岁。多关节型是最常见的表现类型（42.3%）。其他JIA亚型的频率如下：少关节型37.1%，全身型8.9%，附着点炎相关关节炎（ERA）10.8%，银屑病关节炎0.9%。膝关节（74.2%）和踝关节（54.0%）是最常受累的关节。4.2%的患者发现有葡萄膜炎。11.7%的患者抗核抗体呈阳性，2.8%的患者HLA - B27呈阳性。在最后一次随访时，57例（26.7%）患者有活动性疾病。
结论
在本研究中，多关节型JIA是主要亚型，与以往研究相比，抗核抗体阳性或葡萄膜炎的患者较少。《希波克拉底》2015年，第19卷（1）：63 - 68页。
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