神经功能受损的极低出生体重儿的认知和运动功能
Cognitive and motor function of neurologically impaired extremely low birth weight children.
作者信息
Bernardo Janine, Friedman Harriet, Minich Nori, Taylor H Gerry, Wilson-Costello Deanne, Hack Maureen
机构信息
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Department of Pediatrics, University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio, USA.
出版信息
Paediatr Child Health. 2015 Aug-Sep;20(6):e33-7. doi: 10.1093/pch/20.6.e33.
BACKGROUND
Rates of neurological impairment among extremely low birth weight children (ELBW [<1 kg]) have decreased since 2000; however, their functioning is unexamined.
OBJECTIVE
To compare motor and cognitive functioning of ELBW children with neurological impairment, including cerebral palsy and severe hypotonia/hypertonia, between two periods: 1990 to 1999 (n=83) and 2000 to 2005 (n=34).
METHODS
Measures of function at 20 months corrected age included the Mental and Psychomotor Developmental Indexes of the Bayley Scales of Infant Development and the Gross Motor Functional Classification System as primary outcomes and individual motor function items as secondary outcomes.
RESULTS
Analysis failed to reveal significant differences for the primary outcomes, although during 2000 to 2005, sitting significantly improved in children with neurological impairment (P=0.003).
CONCLUSION
Decreases in rates of neurological impairment among ELBW children have been accompanied by a suggestion of improved motor function, although cognitive function has not changed.
背景
自2000年以来，极低出生体重儿（ELBW[<1kg]）的神经功能障碍发生率有所下降；然而，他们的功能尚未得到研究。
目的
比较1990年至1999年（n=83）和2000年至2005年（n=34）两个时期患有神经功能障碍（包括脑瘫和严重肌张力低下/亢进）的ELBW儿童的运动和认知功能。
方法
矫正年龄20个月时的功能测量指标包括贝利婴儿发育量表的心理和精神运动发育指数以及粗大运动功能分类系统作为主要结局，个体运动功能项目作为次要结局。
结果
分析未能揭示主要结局的显著差异，尽管在2000年至2005年期间，神经功能障碍儿童的坐位能力有显著改善（P=0.003）。
结论
ELBW儿童神经功能障碍发生率的下降伴随着运动功能改善的迹象，尽管认知功能没有变化。
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