Salih Mohsin, Aljarod Tarake, Ayan Mohamed, Jeffrey Melnick, Shah Bobby H
Internal Medicine Department, St. Luke's Hospital, Chesterfield, MO 63017, USA.
Internal Medicine Department, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Case Rep Med. 2015;2015:543070. doi: 10.1155/2015/543070. Epub 2015 Sep 7.
Silica and silicate mineral dust inhalation can cause a variety of histopathological changes in the lungs and pleura. These include pulmonary silicotic nodules, interstitial infiltrate, fibrosis, and pleural thickening. Pleural effusion is an extremely rare presentation of silicosis. To our best knowledge, there have been only 2 cases of silicosis with pleural effusion reported in medical literature. Herein, we describe a case of a 77-year-old male with almost 50 years' history of occupational silica exposure. He presented with a 4-week history of exertional shortness of breath. He is a lifetime nonsmoker, with no known other significant pulmonary disease. He had chest X-ray which showed a right lung infiltrate and bilateral pleural thickening and effusion. Chest CT showed moderate-sized bilateral pleural effusion and thickening with multiple bilateral intrapulmonary nodules seen. He had undergone extensive workup and was diagnosed with silicosis.
吸入二氧化硅和硅酸盐矿物粉尘可导致肺部和胸膜出现多种组织病理学变化。这些变化包括肺硅结节、间质浸润、纤维化和胸膜增厚。胸腔积液是矽肺极其罕见的表现形式。据我们所知，医学文献中仅报道过2例伴有胸腔积液的矽肺病例。在此，我们描述一例77岁男性病例，其有近50年的职业性二氧化硅接触史。他出现了为期4周的劳力性气短症状。他终生不吸烟，无其他已知的重大肺部疾病。他的胸部X光显示右肺浸润以及双侧胸膜增厚和胸腔积液。胸部CT显示双侧中等量胸腔积液和增厚，并可见多个双侧肺内结节。他接受了全面检查，被诊断为矽肺。
