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利用胸腔积液细胞块元素分析诊断矽肺相关胸腔积液:一例报告

Silicosis-related pleural effusion diagnosed using elemental analysis of the pleural fluid cell block: A case report.

作者信息

Okamoto Shouichi, Kobayashi Isao, Moriyama Hiroshi, Tanimura Mayuka, Kadoya Kotaro, Ienaga Hiroki, Kikuchi Toshiaki, Takahashi Kazuhisa

机构信息

Division of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.

Department of Respiratory Medicine, Koshigaya Municipal Hospital, 10-32, Higashikoshigaya, Koshigaya, Saitama, 343-8577, Japan.

出版信息

Respir Med Case Rep. 2022 May 11;37:101665. doi: 10.1016/j.rmcr.2022.101665. eCollection 2022.

DOI:10.1016/j.rmcr.2022.101665
PMID:35601868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9117916/
Abstract

Pleural disease in silicosis remains an underrecognized entity. Herein, we describe the case of an 85-year-old man with a 20-year history of silica exposure between the ages of 9-28 years. He presented with bilateral exudative pleural effusions, and chest computed tomography revealed typical silicosis findings. Thoracentesis was performed thrice, but did not reveal the cause of effusion. However, pleural fluid cell-block elemental analysis revealed a silicon compound, suggesting that silicosis-related pleural effusion had developed after a long latency period. Therefore, elemental analysis of the pleural fluid cell block may help diagnose occupational lung diseases with pleural effusion.

摘要

矽肺中的胸膜疾病仍是一个未得到充分认识的实体。在此,我们描述了一名85岁男性的病例,他在9至28岁之间有20年的二氧化硅接触史。他出现双侧渗出性胸腔积液,胸部计算机断层扫描显示典型的矽肺表现。进行了三次胸腔穿刺,但未揭示积液原因。然而,胸腔积液细胞块元素分析显示有一种硅化合物,提示矽肺相关胸腔积液在长期潜伏期后发生。因此,胸腔积液细胞块的元素分析可能有助于诊断伴有胸腔积液的职业性肺病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0f3/9117916/c2908a6f2511/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0f3/9117916/e889bc58ba5d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0f3/9117916/c2908a6f2511/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0f3/9117916/e889bc58ba5d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0f3/9117916/c2908a6f2511/gr2.jpg

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