Grolla Elisabetta, Dalla Vestra Michele, Bonanni Luca, Cutolo Ada, Rigo Fausto
Department of Cardiology, Ospedale dell'Angelo, Mestre, 30174 Venezia, Italy.
Angiology Unit, Ospedale dell'Angelo, Mestre, 30174 Venezia, Italy.
Case Rep Cardiol. 2015;2015:607107. doi: 10.1155/2015/607107. Epub 2015 Sep 8.
Idiopathic hypereosinophilic syndrome (HES) is characterized by persistent eosinophilia and eosinophil-mediated organ-system damage. Cardiac thrombosis and thromboembolic complications represent common causes of morbidity and mortality and usually involve cardiac ventricles or mitral and prosthetic valves, while the involvement of the aortic valve is extremely rare in HES. Here we report peculiar multimodality images of an atypical case of extended thrombosis of the aortic valve, complicated by myocardial ischemia and asymptomatic cerebral ischemia, likely due to thrombus embolization, occurring in a 48-year-old man with HES. Prompt anticoagulant and steroid therapy lead to rapid and complete resolution of the thrombotic lesions, allowing preserving the native valve and preventing further embolic events.
特发性嗜酸性粒细胞增多综合征（HES）的特征是持续性嗜酸性粒细胞增多以及嗜酸性粒细胞介导的器官系统损害。心脏血栓形成和血栓栓塞并发症是发病和死亡的常见原因，通常累及心室或二尖瓣及人工瓣膜，而主动脉瓣受累在HES中极为罕见。在此，我们报告了一例48岁患有HES的男性患者，其主动脉瓣广泛血栓形成伴心肌缺血和无症状性脑缺血（可能由于血栓栓塞所致）的非典型病例的特殊多模态影像。及时的抗凝和类固醇治疗使血栓性病变迅速完全消退，得以保留自体瓣膜并预防了进一步的栓塞事件。
