Kulkarni Aditya Atul, Thakur Sanjiv S
Senior Resident, Department of General Surgery, B.J. Government Medical College , Pune, India .
Professor and Head, Department of General Surgery, B.J. Government Medical College , Pune, India .
J Clin Diagn Res. 2015 Aug;9(8):PD03-5. doi: 10.7860/JCDR/2015/14017.6409. Epub 2015 Aug 1.
Malignant tumours of the submandibular salivary glands are rare entities. Most common malignant tumour of submandibular gland is mucoepidermoid carcinoma. Histological finding of squamous cell carcinoma is very rare in submandibular salivary gland. Metastasis from distant primary squamous malignancy, direct invasion from cutaneous or mucosal squamous carcinoma, squamous component of mucoepidermoid carcinoma or primary squamous cell carcinoma of salivary origin are some of the possible causes. Of these, the latter is distinctly uncommon. Primary squamous malignancy is diagnosed only after ruling out other possible explanations. A positive mucin stain in the tumour or synchronous/ metachronous squamous carcinoma elsewhere excludes the diagnosis of a primary carcinoma. Primary squamous carcinoma is seen most commonly in parotid gland and rarely in submandibular gland. We present a case of primary squamous cell carcinoma of right submandibular salivary gland in a 45-year old-man. This case is presented for the rare entity of primary squamous cell carcinoma in submandibular salivary gland.
下颌下涎腺恶性肿瘤是罕见的疾病。下颌下腺最常见的恶性肿瘤是黏液表皮样癌。下颌下涎腺中鳞状细胞癌的组织学表现非常罕见。远处原发性鳞状恶性肿瘤的转移、皮肤或黏膜鳞状细胞癌的直接侵犯、黏液表皮样癌的鳞状成分或涎腺源性原发性鳞状细胞癌是一些可能的原因。在这些原因中，后者明显不常见。只有在排除其他可能的解释后才能诊断原发性鳞状恶性肿瘤。肿瘤中黏液染色阳性或其他部位同时/异时发生鳞状细胞癌可排除原发性癌的诊断。原发性鳞状细胞癌最常见于腮腺，很少见于下颌下腺。我们报告一例45岁男性右下颌下涎腺原发性鳞状细胞癌的病例。本文报告此病例是因为下颌下涎腺原发性鳞状细胞癌实属罕见。
