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一名免疫功能低下的乳腺癌女性出现带状疱疹节段性轻瘫。

Herpes zoster segmental paresis in an immunocompromised breast cancer woman.

作者信息

Rastegar Shirvan, Mahdavi Sadegh Baradaran, Mahmoudi Farhad, Basiri Keivan

机构信息

Department of Orthopedics, Alzahra Hospital, Isfahan University of Medical sciences, Isfahan, Iran.

Medical Students' Research Center, Isfahan University of Medical sciences, Isfahan, Iran ; Neurosciences Research Center, Isfahan University of Medical sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2015 Aug 10;4:170. doi: 10.4103/2277-9175.162547. eCollection 2015.

Abstract

Herpes zoster is an infectious disease with neurological complications caused by reactivation of varicella zoster virus in dorsal root ganglia of spinal cord which is also known as "Shingles." Suppression of immune system is the major predisposing factor for reactivation of latent virus. Disease is mainly characterized by rash, vesicles and pain along one or more dermatomes which are innervated from one or more spinal nerve roots. Complications may be present after a while despite of patient treatment. Motor involvement is included. Some previous studies showed segmental zoster paresis as a rare complication, a few weeks after first presentation, among immunocompetent individuals. We present post herpetic motor involvement of C5 and C6 in a 59-year-old woman who underwent chemotherapy and radiotherapy due to breast cancer, manifesting left upper limb weakness and paresis, 6 months after left partial mastectomy. Segmental paresis of zoster virus should be considered as a cause of motor impairment in an immunocompromised person suffering from shingles.

摘要

带状疱疹是一种由脊髓背根神经节中水痘-带状疱疹病毒再激活引起的具有神经并发症的传染病,也被称为“缠腰龙”。免疫系统抑制是潜伏病毒再激活的主要诱发因素。该病主要特征为沿一个或多个由一个或多个脊神经根支配的皮节出现皮疹、水疱和疼痛。尽管患者接受了治疗,但一段时间后仍可能出现并发症,包括运动受累。一些先前的研究表明,在免疫功能正常的个体中,节段性带状疱疹轻瘫是一种罕见的并发症,出现在首次发病后的几周。我们报告了一名59岁因乳腺癌接受化疗和放疗的女性,在左乳部分切除术后6个月出现C5和C6节段的疱疹后运动受累,表现为左上肢无力和轻瘫。对于患有带状疱疹的免疫功能低下者,应考虑带状疱疹病毒节段性轻瘫是运动功能障碍的一个原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bc7/4581133/458a6b54a4d7/ABR-4-170-g001.jpg

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