Perez Lizeth, Ghang Yoo-Jin, Williams Preston B, Wang Yinsheng, Cheng Quan, Hooley Richard J
Department of Chemistry, University of California-Riverside , Riverside, California 92521, United States.
Langmuir. 2015 Oct 20;31(41):11152-7. doi: 10.1021/acs.langmuir.5b03124. Epub 2015 Oct 6.
Water-soluble deep cavitands embedded in a supported lipid bilayer are capable of anchoring ATRP initiator molecules for the in situ synthesis of primary amine-containing polymethacrylate patches at the water:membrane interface. These polymers can be derivatized in situ to incorporate fluorescent reporters, allow selective protein recognition, and can be applied to the immobilization of nonadherent cells at the bilayer interface.
嵌入支撑脂质双分子层中的水溶性深层穴状配体能够锚定原子转移自由基聚合（ATRP）引发剂分子，用于在水与膜的界面原位合成含伯胺的聚甲基丙烯酸酯贴片。这些聚合物可原位衍生化，以引入荧光报告基团，实现选择性蛋白质识别，并可用于在双分子层界面固定非粘附细胞。
