Handra-Luca Adriana, Haddar Djamel, Morin Anne-Sophie
Service d'Anatomie Pathologique, Assistance Publique - Hopitaux de Paris (AP-HP), Universitx00E9; Paris Nord Sorbonne Citx00E9;, Bobigny, France.
Med Princ Pract. 2016;25(1):96-8. doi: 10.1159/000441455. Epub 2015 Oct 30.
To report a case of a schwannoma of nasopalpebral location, occurring in a human immunodeficiency virus (HIV)-positive patient.
A 55-year-old man presented with a nasopalpebral painless tumefaction, pneumopathy and HIV-related immunodepression after stopping combination antiretroviral therapy. Magnetic resonance imaging showed subcutaneous masses, with contrast enhancement of the left nose pyramid, internal cantus and inferior palpebral area, suspicious of Kaposi sarcoma. The resected specimen showed schwannoma histology, with tumor cells expressing S100 protein and WT1.
The features of a rare case of facial schwannoma of nasopalpebral location in an HIV-positive patient are reported. The diagnosis may be difficult before microscopic examination, with imaging features suggesting a Kaposi sarcoma.
报告一例发生于人类免疫缺陷病毒（HIV）阳性患者的鼻睑部神经鞘瘤病例。
一名55岁男性在停止联合抗逆转录病毒治疗后，出现鼻睑部无痛性肿物、肺病及HIV相关免疫抑制。磁共振成像显示皮下肿块，左侧鼻锥体、内眦和下睑区域有对比增强，怀疑为卡波西肉瘤。切除标本显示为神经鞘瘤组织学表现，肿瘤细胞表达S100蛋白和WT1。
报告了一例HIV阳性患者鼻睑部罕见面部神经鞘瘤的特征。在显微镜检查前诊断可能困难，影像学特征提示为卡波西肉瘤。
