Horton William B, Weeks Andrew Q, Rhinewalt J Matthew, Ballard Richard D, Asher Frederick H
From the Department of Medicine, University of Mississippi Medical Center, Jackson.
South Med J. 2015 Oct;108(10):596-8. doi: 10.14423/SMJ.0000000000000348.
To determine the effects of a guideline-derived resident educational program on inpatient glycemic control and length of hospital stay (LOS).
We compared the following variables before and after resident education: percentage of patients on basal-plus-bolus regimens, mean fingerstick glucose (FSG), LOS, and rates of hypoglycemia (FSG<70 mg/dL) and severe hypoglycemia (FSG<40 mg/dL). A two-tailed t test was used for all continuous data and P<0.05 was considered statistically significant.
After education, more patients (23% vs 8%; P=0.024) were placed on basal-plus-bolus regimens. We observed a decrease in mean FSG (158.7 mg/dL vs 165.1 mg/dL; P=0.028) and LOS (5.03 days vs 6.98 days; P=0.042). Rates of hypoglycemia (4.6% vs 1.5%; P<0.001) and severe hypoglycemia (0.71% vs 0.24%; P=0.089) increased.
Our resident educational program significantly increased the number of patients receiving guideline-based inpatient insulin therapy and was associated with a reduction in mean FSG and LOS. Rates of hypoglycemia showed a statistically significant increase, whereas rates of severe hypoglycemia did not. Larger multicenter studies with adjustment for potential confounders are needed to further assess the impact of educational interventions on inpatient glycemic control.
确定一项基于指南的住院医师教育计划对住院患者血糖控制及住院时间(LOS)的影响。
我们比较了住院医师教育前后的以下变量:接受基础加餐时胰岛素治疗方案的患者百分比、平均指尖血糖(FSG)、住院时间以及低血糖(FSG<70 mg/dL)和严重低血糖(FSG<40 mg/dL)发生率。所有连续性数据采用双侧t检验,P<0.05被认为具有统计学意义。
教育后,更多患者(23%对8%;P=0.024)接受了基础加餐时胰岛素治疗方案。我们观察到平均FSG下降(158.7 mg/dL对165.1 mg/dL;P=0.028),住院时间缩短(5.03天对6.98天;P=0.042)。低血糖发生率(4.6%对1.5%;P<0.001)和严重低血糖发生率(0.71%对0.24%;P=0.089)增加。
我们的住院医师教育计划显著增加了接受基于指南的住院胰岛素治疗的患者数量,并与平均FSG和住院时间的减少相关。低血糖发生率有统计学意义的增加,而严重低血糖发生率没有。需要进行更大规模的多中心研究并对潜在混杂因素进行校正,以进一步评估教育干预对住院患者血糖控制的影响。