Kumar Kamlesh, Woortman Albert J J, Loos Katja
Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747, AG, Groningen, The Netherlands.
Macromol Rapid Commun. 2015 Dec;36(23):2097-101. doi: 10.1002/marc.201500343. Epub 2015 Oct 5.
A new class of rod-coil block copolymers is synthesized by chemoenzymatic polymerization. In the first step, maltoheptaose, which acts as a primer for the synthesis of amylose, is attached to poly(2-vinyl pyridine) (P2 VP). The enzymatic polymerization of maltoheptaose is carried out by phosphorylase to obtain amylose-b-P2 VP block copolymers. The block copolymer is characterized by Fourier transform infrared spectroscopy, nuclear magnetic resonance, gel permeation chromatography, and wide-angle X-ray scattering techniques. The designed molecules combine the inclusion complexation ability of amylose with the supramolecular complexation ability of P2 VP and therefore this kind of rod-coil block copolymers can be used to generate well-organized novel self-assembled structures.
通过化学酶促聚合反应合成了一类新型的棒-线圈嵌段共聚物。第一步，将作为直链淀粉合成引物的麦芽七糖连接到聚（2-乙烯基吡啶）（P2 VP）上。通过磷酸化酶进行麦芽七糖的酶促聚合反应，以获得直链淀粉-b-P2 VP嵌段共聚物。该嵌段共聚物通过傅里叶变换红外光谱、核磁共振、凝胶渗透色谱和广角X射线散射技术进行表征。所设计的分子将直链淀粉的包合络合能力与P2 VP的超分子络合能力结合起来，因此这种棒-线圈嵌段共聚物可用于生成有序的新型自组装结构。
