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嗜酸性粒细胞性食管炎患者的食管运动功能受损。

Impaired esophageal motor function in eosinophilic esophagitis.

作者信息

Santander Cecilio, Chavarría-Herbozo Carlos M, Becerro-González Irene, Burgos-Santamaría Diego

机构信息

Aparato Digestivo, HU La Princesa, españa.

Aparato Digestivo, Hospital de La Princesa, España.

出版信息

Rev Esp Enferm Dig. 2015 Oct;107(10):622-9. doi: 10.17235/reed.2015.3801/2015.

DOI:10.17235/reed.2015.3801/2015
PMID:26437981
Abstract

Eosinophilic esophagitis is a chronic immunoallergic inflammatory disease of the esophagus that represents a major cause of digestive morbidity among the pediatric and young adult populations. Despite the fact that key symptoms in adults include dysphagia and food impaction, many patients lack structural changes in the esophagus to account for their complaints, which suggests the presence of underlying motor disorders and esophageal distensibility impairment. In the last few years the esophageal motility of these patients has been studied using various approaches, most particularly high-resolution manometry, ambulatory manometry, and impedance planimetry. This review focuses on the most relevant findings and scientific evidence regarding esophageal motor disorders in eosinophilic esophagitis.

摘要

嗜酸性粒细胞性食管炎是一种食管慢性免疫过敏性炎症性疾病,是儿童和青年人群消化系统发病的主要原因。尽管成年人的主要症状包括吞咽困难和食物嵌塞,但许多患者食管并无结构改变来解释其症状,这表明存在潜在的运动障碍和食管扩张功能受损。在过去几年中,已采用多种方法研究了这些患者的食管动力,最主要的是高分辨率测压法、动态测压法和阻抗平面测量法。本综述重点关注嗜酸性粒细胞性食管炎中食管运动障碍的最相关研究结果和科学证据。

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