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土耳其绝经后女性低骨密度吸烟情况评估。

Assessment of smoking for low bone mineral density in postmenopausal Turkish women.

作者信息

Ugurlu Ugur, Nayki Umit, Nayki Cenk, Ulug Pasa, Kulhan Mehmet, Yildirim Yusuf

机构信息

Department of Obstetrics and Gynecology, Tepecik Training and Research Hospital, Izmir, Turkey.

Department of Obstetrics and Gynecology, School of Medicine, Erzincan University, Erzincan, Turkey.

出版信息

Wien Klin Wochenschr. 2016 Feb;128(3-4):114-9. doi: 10.1007/s00508-015-0867-7. Epub 2015 Oct 5.

Abstract

OBJECTIVE

To investigate the effect of cigarette smoking on bone mineral density (BMD) in postmenopausal Turkish women.

STUDY DESIGN

A total of 175 postmenopausal Turkish women admitted to Tepecik Training and Research Hospital for a routine menopausal checkup were included in this study. All participants completed a questionnaire regarding their age, educational status, parity, number of abortus, time since menopause, caffeine intake, tobacco use, alcohol consumption, history of a previous fracture related to trauma, and taking any medication for menopause and osteoporosis. Of all subjects, 23.3% (n = 39) were smokers and 77.7% (n = 136) were nonsmokers. T-scores and Z-scores of vertebra and femur neck were assessed using dual energy X-ray absorptiometry (DXA). For analyzing the results, Student t-test, one-way ANOVA, Mann-Whitney U test, Pearson correlation, and Kruskal-Wallis test were performed.

RESULTS

Femur T-scores (- 0.78 ± 1.07 vs. - 0.32 ± 1.56) and vertebra T-scores (- 2.26 ± 1.23 vs. - 1.82 ± 1.04) were significantly lower in smoking women than nonsmoking women (p < 0.05). However, there were no significant difference between duration of smoking, number of cigarettes consumed per day, and BMD (p > 0.05) CONCLUSION: Cigarette smoking is one of the modifiable risk factors influencing bone density in postmenopausal Turkish women. "Cessation of cigarette" should be recommended for lifestyle modifications to prevent postmenopausal osteoporosis.

摘要

目的

探讨吸烟对绝经后土耳其女性骨密度(BMD)的影响。

研究设计

本研究纳入了175名因进行常规绝经检查而入住特佩奇克培训与研究医院的绝经后土耳其女性。所有参与者均完成了一份关于其年龄、教育程度、产次、流产次数、绝经时间、咖啡因摄入量、吸烟情况、饮酒量、既往创伤相关骨折史以及是否服用任何绝经和骨质疏松药物的问卷。在所有受试者中,23.3%(n = 39)为吸烟者,77.7%(n = 136)为非吸烟者。使用双能X线吸收法(DXA)评估腰椎和股骨颈的T值和Z值。为分析结果,进行了学生t检验、单因素方差分析、曼-惠特尼U检验、皮尔逊相关性分析和克鲁斯卡尔-沃利斯检验。

结果

吸烟女性的股骨T值(-0.78±1.07 vs. -0.32±1.56)和腰椎T值(-2.26±1.23 vs. -1.82±1.04)显著低于非吸烟女性(p < 0.05)。然而,吸烟持续时间、每日吸烟量与骨密度之间无显著差异(p > 0.05)。结论:吸烟是影响绝经后土耳其女性骨密度的可改变风险因素之一。应建议“戒烟”以改变生活方式,预防绝经后骨质疏松症。

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