他汀类药物通过调节凋亡和自噬活性降低格雷夫斯病患者的眼眶病风险。
Statin reduces orbitopathy risk in patients with Graves' disease by modulating apoptosis and autophagy activities.
作者信息
Bifulco Maurizio, Ciaglia Elena
机构信息
Department of Medicine and Surgery, University of Salerno, Via Salvatore Allende, 84081, Baronissi, Salerno, Italy.
出版信息
Endocrine. 2016 Sep;53(3):649-50. doi: 10.1007/s12020-015-0762-z. Epub 2015 Oct 5.
PMID:26438397
Abstract
Statins use has been associated with reduced risk for developing orbitopathy among patients with Graves' disease. We hypothesize that statin reduces orbitopathy risk mainly by modulating both apoptosis and autophagy activities in patients with Graves' disease.
摘要
他汀类药物的使用与格雷夫斯病患者发生眼眶病的风险降低有关。我们推测，他汀类药物主要通过调节格雷夫斯病患者的细胞凋亡和自噬活性来降低眼眶病风险。
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