Ross C B, H'Doubler W Z, Sharp K W, Potts J R
Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232.
Am Surg. 1989 Jan;55(1):64-70.
The management of benign biliary strictures continues to represent one of the most difficult problems in the practice of general surgery. Twenty-eight consecutive patients with benign strictures treated between 1972 and 1987 are reviewed in this report. Stricture etiology was iatrogenic in 13 patients, pancreatitic in 11, idiopathic in three, and traumatic in one. The authors performed 27 operations and three percutaneous transhepatic balloon dilatations in the treatment of these patients. Operative morbidity was 18 per cent; there were no operative deaths. Treatment was successful in 23 of 28 patients with a mean followup of four years, and four of the five patients with initially unsuccessful results have undergone successful remedial operations. Roux-en-Y biliary enteric diversion procedures have been most successful in these patients: seven patients with Roux-en-Y choledochojejunostomy without recurrence (mean followup of 62 months) and eight patients with Roux-en-Y hepaticojejunostomy with a success rate of 87.5 per cent (mean followup of 50 months). Two patients underwent three percutaneous transhepatic balloon dilatations; one has had a good result with short followup and the other failed on two occasions and has required a remedial operation. Benign biliary strictures have multiple etiologies. Therapeutic approaches, which now include nonoperative procedures, must be tailored to the needs of individual patients. The potential for recurrence is always present. Longterm followup remains essential in the management of patients with this disorder.
良性胆管狭窄的处理仍然是普通外科实践中最棘手的问题之一。本报告回顾了1972年至1987年间连续治疗的28例良性狭窄患者。狭窄病因中,医源性的有13例,胰腺炎相关的有11例,特发性的有3例,创伤性的有1例。作者对这些患者进行了27次手术和3次经皮肝穿刺球囊扩张术。手术并发症发生率为18%;无手术死亡病例。28例患者中有23例治疗成功,平均随访4年,最初治疗未成功的5例患者中有4例已接受成功的补救手术。Roux-en-Y胆肠转流术在这些患者中最为成功:7例行Roux-en-Y胆总管空肠吻合术的患者无复发(平均随访62个月),8例行Roux-en-Y肝管空肠吻合术的患者成功率为87.5%(平均随访50个月)。2例患者接受了3次经皮肝穿刺球囊扩张术;1例随访时间短但效果良好,另1例两次手术均失败,需要进行补救手术。良性胆管狭窄有多种病因。现在包括非手术方法在内的治疗方法必须根据个体患者的需求进行调整。复发的可能性始终存在。对这类疾病患者的管理进行长期随访仍然至关重要。