University of Lyon-1 Villeurbanne , CNRS, UMR 5007, LAGEP-CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France.
Department of Chemistry, Faculty of Science, Mahidol University , Phyathai, Bangkok 10400, Thailand.
ACS Appl Mater Interfaces. 2015 Oct 28;7(42):23373-86. doi: 10.1021/acsami.5b07515. Epub 2015 Oct 13.
Fluorescent-magnetic particles (FMPs) play important roles in modern materials, especially as nanoscale devices in the biomedical field. The interesting features of FMPs are attributed to their dual detection ability, i.e., fluorescent and magnetic modes. Functionalization of FMPs can be performed using several types of polymers, allowing their use in various applications. The synergistic potentials for unique multifunctional, multilevel targeting nanoscale devices as well as combination therapies make them particularly attractive for biomedical applications. However, the synthesis of FMPs is challenging and must be further developed. In this review article, we summarized the most recent representative works on polymer-based FMP systems that have been applied particularly in the bioanalytical field.
荧光磁性粒子（FMPs）在现代材料中扮演着重要的角色，尤其是在生物医学领域作为纳米级器件。FMPs 的有趣特性归因于其双重检测能力，即荧光和磁性模式。FMPs 的功能化可以使用几种类型的聚合物来完成，这使得它们可以应用于各种应用。作为独特的多功能、多层次靶向纳米级器件以及联合治疗的协同潜力，使它们在生物医学应用中特别有吸引力。然而，FMPs 的合成具有挑战性，需要进一步发展。在这篇综述文章中，我们总结了最近在聚合物基 FMP 系统方面的代表性工作，这些工作特别应用于生物分析领域。
