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磁性荧光量子点纳米复合材料在食品污染物分析中的应用:当前的挑战与机遇。

Magnetic Fluorescent Quantum Dots Nanocomposites in Food Contaminants Analysis: Current Challenges and Opportunities.

机构信息

Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory for Food Quality and Safety, Beijing 100193, China.

Department of Veterinary Pharmacology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.

出版信息

Int J Mol Sci. 2022 Apr 7;23(8):4088. doi: 10.3390/ijms23084088.

Abstract

The presence of food contaminants can cause foodborne illnesses, posing a severe threat to human health. Therefore, a rapid, sensitive, and convenient method for monitoring food contaminants is eagerly needed. The complex matrix interferences of food samples and poor performance of existing sensing probes bring significant challenges to improving detection performances. Nanocomposites with multifunctional features provide a solution to these problems. The combination of the superior characteristics of magnetic nanoparticles (MNPs) and quantum dots (QDs) to fabricate magnetic fluorescent quantum dots (MNPs@QDs) nanocomposites are regarded as an ideal multifunctional probe for food contaminants analysis. The high-efficiency pretreatment and rapid fluorescence detection are concurrently integrated into one sensing platform using MNPs@QDs nanocomposites. In this review, the contemporary synthetic strategies to fabricate MNPs@QDs, including hetero-crystalline growth, template embedding, layer-by-layer assembly, microemulsion technique, and one-pot method, are described in detail, and their advantages and limitations are discussed. The recent advances of MNPs@QDs nanocomposites in detecting metal ions, foodborne pathogens, toxins, pesticides, antibiotics, and illegal additives are comprehensively introduced from the perspectives of modes and detection performances. The review ends with current challenges and opportunities in practical applications and prospects in food contaminants analysis, aiming to promote the enthusiasm for multifunctional sensing platform research.

摘要

食物污染物的存在会导致食源性疾病,对人类健康构成严重威胁。因此,迫切需要一种快速、敏感、方便的方法来监测食物污染物。食物样品复杂的基质干扰和现有传感探针的性能不佳给提高检测性能带来了重大挑战。具有多功能特性的纳米复合材料为解决这些问题提供了一种解决方案。将磁性纳米粒子(MNPs)和量子点(QDs)的优异特性结合起来,制备磁性荧光量子点(MNPs@QDs)纳米复合材料,被认为是分析食物污染物的理想多功能探针。MNPs@QDs 纳米复合材料将高效预处理和快速荧光检测集成到一个传感平台中。在这篇综述中,详细描述了制备 MNPs@QDs 的当代合成策略,包括异质晶生长、模板嵌入、层层组装、微乳液技术和一锅法,并讨论了它们的优缺点。从模式和检测性能两个方面,全面介绍了 MNPs@QDs 纳米复合材料在检测金属离子、食源性病原体、毒素、农药、抗生素和非法添加剂方面的最新进展。最后,本文讨论了在实际应用中的当前挑战和机遇以及在食物污染物分析中的前景,旨在促进多功能传感平台研究的积极性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1735/9028821/db2d5609ab37/ijms-23-04088-g001.jpg

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