Hashimoto Sayuki, Mizutani Erika, Suzuki Maiko, Yoshida Akihiro, Naito Michitaka
Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University.
J Nutr Sci Vitaminol (Tokyo). 2015;61(4):299-305. doi: 10.3177/jnsv.61.299.
We examined the acute effects of postprandial aerobic exercise on glucose and lipid metabolism following cookie ingestion. Fifteen healthy young women with a sedentary lifestyle, normal weight and apolipoprotein E3/3 participated. After a 12-h overnight fast, each subject ingested a cookie (1.53 g/kg, Meal Test C) and then performed two trials, one with postprandial exercise (E trial) and one without exercise (C trial), in a randomized crossover design. A single 30-min bout of walking exercise was performed 20 min after the cookie intake. Venous blood samples were drawn before (0 h) and 20 min and 1, 2, 4, and 6 h after cookie ingestion. The Δglucose concentration was not significantly different between the two trials, but the Δinsulin concentration at 1 h and the incremental area under the curve (IAUC) (0-2 h)-insulin in the E trial were significantly lower than in the C trial. The ratio of glucose/insulin at 1 h was significantly higher in the E trial than in the C trial. The ΔTG, ΔRLP-TG, ΔapoB48 and ΔRemL-C concentrations at 1 h in the E trial were significantly higher than in the C trial. The IAUC (0-2 h)-apoB48 in the E trial was significantly larger than in the C trial. Postprandial exercise showed an insulin-sparing effect following the cookie ingestion by increasing insulin sensitivity. However, postprandial exercise transiently stimulated the secretion of exogenous apoB48-containing lipoprotein during the early period, and no further effects were observed. These results suggest that postprandial aerobic exercise is effective for the promotion of postprandial carbohydrate metabolism, but not lipidemia.
我们研究了餐后有氧运动对摄入饼干后葡萄糖和脂质代谢的急性影响。15名久坐不动、体重正常且载脂蛋白E3/3的健康年轻女性参与了研究。在禁食12小时过夜后，每位受试者摄入一块饼干（1.53克/千克，餐食测试C），然后采用随机交叉设计进行两项试验，一项为餐后运动试验（E试验），一项为无运动试验（C试验）。在摄入饼干20分钟后进行一次30分钟的步行运动。在摄入饼干前（0小时）以及摄入后20分钟、1小时、2小时、4小时和6小时采集静脉血样。两次试验之间的Δ葡萄糖浓度无显著差异，但E试验中1小时的Δ胰岛素浓度以及曲线下增量面积（IAUC）（0 - 2小时）-胰岛素显著低于C试验。E试验中1小时的葡萄糖/胰岛素比值显著高于C试验。E试验中1小时的Δ甘油三酯（TG）、Δ残粒样脂蛋白 - TG（RLP - TG）、Δ载脂蛋白B48（apoB48）和Δ残粒样脂蛋白胆固醇（RemL - C）浓度显著高于C试验。E试验中IAUC（0 - 2小时）-apoB48显著大于C试验。餐后运动通过提高胰岛素敏感性，在摄入饼干后显示出胰岛素节省效应。然而，餐后运动在早期短暂刺激了含外源性apoB48的脂蛋白分泌，未观察到进一步影响。这些结果表明，餐后有氧运动对促进餐后碳水化合物代谢有效，但对血脂异常无效。
