通过钯催化的烷氧基二硼与未保护的邻溴苄醇的交叉偶联反应一锅法合成苯并硼唑衍生物。

One-pot synthesis of benzoxaborole derivatives from the palladium-catalyzed cross-coupling reaction of alkoxydiboron with unprotected o-bromobenzylalcohols.

作者信息

Zhu Jianan, Wei Ying, Lin Dongqing, Ou Changjin, Xie Linghai, Zhao Yu, Huang Wei

机构信息

Centre for Molecular Systems and Organic Devices (CMSOD), Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China.

Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, China.

出版信息

Org Biomol Chem. 2015 Dec 14;13(46):11362-8. doi: 10.1039/c5ob01781e.

DOI:10.1039/c5ob01781e

PMID:26440765

Abstract

Under very mild conditions, functionalized benzoxaborole derivatives were prepared in good to excellent yields via a palladium-catalyzed Miyaura borylation reaction of readily available unprotected o-bromobenzylalcohols, and bis(pinacolato)diboron (B2pin2) without the assistance of an acid. Blue-light-emitting materials based on spiro benzoxaborole building blocks have been obtained with potential applications in organic electronics and biomedicine.

摘要

在非常温和的条件下，通过钯催化的、无需酸辅助的、由易得的未保护邻溴苯甲醇与双(频哪醇合)二硼(B2pin2)进行的宫浦硼化反应，以良好至优异的产率制备了功能化苯并硼唑衍生物。基于螺苯并硼唑结构单元的蓝光发射材料已被制备出来，在有机电子学和生物医学领域具有潜在应用。