Armstrong Lawrence E, Johnson Evan C, McKenzie Amy L, Muñoz Colleen X
University of Connecticut, Department of Kinesiology, Human Performance Laboratory, Storrs, Connecticut, USA; University of Connecticut, Department of Nutritional Sciences, Storrs, Connecticut, USA.
University of Connecticut, Department of Kinesiology, Human Performance Laboratory, Storrs, Connecticut, USA.
Nutrition. 2016 Jan;32(1):79-82. doi: 10.1016/j.nut.2015.07.013. Epub 2015 Aug 15.
The physiological regulation of total body water and fluid concentrations is complex and dynamic. The human daily water requirement varies because of differences in body size, dietary solute load, exercise, and activities. Although chronically concentrated urine increases the risk of renal diseases, an empirical method to determine inadequate daily water consumption has not been described for any demographic group; instead, statistical analyses are applied to estimate nutritional guidelines (i.e., adequate intake). This investigation describes a novel empirical method to determine the 24-h total fluid intake (TFI; TFI = water + beverages + moisture in food) and 24-h urine volume, which correspond to inadequate 24-h water intake (defined as urine osmolality of 800 mOsm/kg; U800).
Healthy young women (mean ± standard deviation; age, 20 ± 2 y, mass, 60.8 ± 11.7 kg; n = 28) were observed for 7 consecutive days. A 24-h urine sample was analyzed for volume and osmolality. Diet records were analyzed to determine 24-h TFI.
For these 28 healthy young women, the U800 corresponded to a TFI ≥2.4 L/d (≥39 mL/kg/d) and a urine volume ≥1.3 L/d.
The U800 method could be employed to empirically determine 24-h TFI and 24-h urine volumes that correspond to inadequate water intake in diverse demographic groups, residents of specific geographic regions, and individuals who consume specialized diets or experience large daily water turnover. Because laboratory expertise and instrumentation are required, this technique provides greatest value in research and clinical settings.
全身水和液体浓度的生理调节复杂且动态变化。由于体型、饮食溶质负荷、运动及活动的差异,人类每日需水量各不相同。尽管长期尿液浓缩会增加患肾脏疾病的风险,但尚未有针对任何人群描述确定每日饮水量不足的经验性方法;相反,采用统计分析来估计营养指南(即适宜摄入量)。本研究描述了一种新颖的经验性方法,用于确定24小时总液体摄入量(TFI;TFI = 水 + 饮料 + 食物中的水分)和24小时尿量,这两者对应着24小时饮水量不足(定义为尿渗透压为800 mOsm/kg;U800)。
对28名健康年轻女性(平均 ± 标准差;年龄,20 ± 2岁,体重,60.8 ± 11.7 kg)连续观察7天。分析24小时尿液样本的体积和渗透压。分析饮食记录以确定24小时TFI。
对于这28名健康年轻女性,U800对应TFI≥2.4 L/天(≥39 mL/kg/天)且尿量≥1.3 L/天。
U800方法可用于凭经验确定不同人群、特定地理区域居民以及食用特殊饮食或每日水分周转量大的个体中与饮水不足相对应的24小时TFI和24小时尿量。由于需要实验室专业知识和仪器设备,该技术在研究和临床环境中具有最大价值。