Moss N G
Department of Physiology, UNC School of Medicine, Chapel Hill.
Miner Electrolyte Metab. 1989;15(1-2):59-65.
The characteristics of afferent renal nerves are described. Renal baroreceptors are excited by increases in renal arterial pressure, venous pressure or interstitial pressure. Increases in intrapelvic pressure also excite renal afferent nerves though these have not been dissociated from renal tissue pressure receptors or renal chemoreceptors which are also excited by increased intrapelvic pressure with urine. The renal chemoreceptors are excited by renal ischemia, backflow of urine into the renal pelvis and pelvic perfusion with solutions of KCl. Injections of bradykinin and capsaicin also activate these receptors. These sensitivities are discussed with respect to other visceral afferent nerves and their role in renal nociception.
本文描述了肾传入神经的特征。肾动脉压、静脉压或间质压升高可兴奋肾压力感受器。肾盂内压升高也可兴奋肾传入神经，不过这些神经与肾组织压力感受器或肾化学感受器尚未区分开来，而后者也会因肾盂内尿液压力升高而兴奋。肾缺血、尿液反流至肾盂以及用氯化钾溶液灌注肾盂可兴奋肾化学感受器。注射缓激肽和辣椒素也可激活这些感受器。文中讨论了这些感受器相对于其他内脏传入神经的敏感性及其在肾伤害感受中的作用。
