Sheehan David V, Herman Barry K
Department of Psychiatry and Behavioral Health, University of South Florida College of Medicine, Tampa (Dr Sheehan), and Shire Development LLC, Wayne, Pennsylvania (Dr Herman).
Prim Care Companion CNS Disord. 2015 Apr 23;17(2). doi: 10.4088/PCC.14r01732. eCollection 2015.
Although binge eating disorder (BED) is the most prevalent eating disorder, the impact of untreated BED is underappreciated. This review describes the relationship of BED to physical and mental health, quality of life, and functionality.
PubMed searches were conducted on March 21, 2014; searches were limited to English-language research articles, meta-analyses, and reviews published between January 1, 2003 and March 21, 2014. Search terms included (binge eating OR binge-eating OR binge eating disorder) AND (cardiovascular OR metabolic OR metabolic syndrome OR gastrointestinal OR health OR rehabilitation OR recovery OR sleep OR pregnancy OR quality of life OR functional impairment OR activities of daily living OR QoL OR SF-12 OR ED-5D OR SF-36 OR psychosocial OR depressive OR anxiety OR self-esteem OR suicidality OR suicide OR productivity OR family).
STUDY SELECTION/DATA EXTRACTION: Of 326 identified publications, 43 were relevant to the topic and reported on the association of BED with psychiatric and medical comorbidities, quality of life, and functional outcomes.
Individuals diagnosed with BED have increased rates of mental health comorbidities (eg, depression and anxiety) and more pronounced medical impairments (eg, cardiovascular disorders) compared with individuals without BED. BED is also associated with functional impairment and reduced quality of life.
Binge eating disorder is associated with impairments in physical and mental health, which can decrease quality of life and functionality and lead to increased health care utilization and decreased productivity. However, some caution is warranted in interpreting these findings because it remains unclear whether BED is an antecedent condition, a complication associated with a comorbid psychiatric condition, or an unrelated feature that occurs concurrently with these comorbidities and impairments. Much of the research on BED is based on observational or epidemiologic studies. Controlled studies are needed to clearly define the long-term impairments associated with BED.
尽管暴饮暴食症（BED）是最常见的饮食失调症，但未经治疗的BED的影响却未得到充分认识。本综述描述了BED与身心健康、生活质量和功能的关系。
于2014年3月21日进行了PubMed搜索；搜索仅限于2003年1月1日至2014年3月21日期间发表的英文研究文章、荟萃分析和综述。搜索词包括（暴饮暴食或暴饮暴食症或暴饮暴食障碍）以及（心血管或代谢或代谢综合征或胃肠道或健康或康复或恢复或睡眠或妊娠或生活质量或功能损害或日常生活活动或QoL或SF - 12或ED - 5D或SF - 36或心理社会或抑郁或焦虑或自尊或自杀倾向或自杀或生产力或家庭）。
研究选择/数据提取：在326篇已识别的出版物中，43篇与该主题相关，并报告了BED与精神和医学合并症、生活质量及功能结局的关联。
与未患BED的个体相比，被诊断患有BED的个体心理健康合并症（如抑郁症和焦虑症）的发生率更高，医学损害（如心血管疾病）也更明显。BED还与功能损害和生活质量下降有关。
暴饮暴食症与身心健康损害相关，这可能会降低生活质量和功能，并导致医疗保健利用率增加和生产力下降。然而，在解释这些发现时需谨慎，因为尚不清楚BED是一种先行状况、与合并精神疾病相关的并发症，还是与这些合并症和损害同时出现的无关特征。关于BED的许多研究基于观察性或流行病学研究。需要进行对照研究以明确界定与BED相关的长期损害。
