Ilves Pilvi, Laugesaar Rael, Loorits Dagmar, Kolk Anneli, Tomberg Tiiu, Lõo Silva, Talvik Inga, Kahre Tiina, Talvik Tiina
Radiology Clinic of Tartu University Hospital, Tartu, Estonia Department of Radiology, University of Tartu, Tartu, Estonia
Department of Pediatrics, University of Tartu, Tartu, Estonia Children's Clinic of Tartu University Hospital, Tartu, Estonia.
J Child Neurol. 2016 Apr;31(5):621-8. doi: 10.1177/0883073815609149. Epub 2015 Oct 7.
It is unknown why some infants with perinatal stroke present clinical symptoms late during infancy and will be identified as infants with presumed perinatal stroke. The risk factors and clinical and radiological data of 42 infants with presumed perinatal stroke (69% with periventricular venous infarction and 31% with arterial ischemic stroke) from the Estonian Pediatric Stroke Database were reviewed. Children with presumed perinatal stroke were born at term in 95% of the cases and had had no risk factors during pregnancy in 43% of the cases. Children with periventricular venous infarction were born significantly more often (82%) vaginally (P = .0213) compared to children with arterial stroke (42%); nor did they require resuscitation (P = .0212) or had any neurological symptoms after birth (P = .0249). Periventricular venous infarction is the most common type of lesion among infants with the presumed perinatal stroke. Data suggest that the disease is of prenatal origin.
目前尚不清楚为什么一些围产期卒中的婴儿在婴儿期晚期才出现临床症状，并被诊断为疑似围产期卒中的婴儿。对爱沙尼亚儿科卒中数据库中42例疑似围产期卒中婴儿（69%为脑室周围静脉梗死，31%为动脉缺血性卒中）的危险因素、临床和放射学数据进行了回顾。95%的疑似围产期卒中儿童足月出生，43%的儿童在孕期无危险因素。与动脉性卒中儿童（42%）相比，脑室周围静脉梗死儿童经阴道分娩的比例显著更高（82%）（P = .0213）；他们也不需要复苏（P = .0212），出生后也没有任何神经症状（P = .0249）。脑室周围静脉梗死是疑似围产期卒中婴儿中最常见的病变类型。数据表明该疾病起源于产前。
