Kuna Anna, Gajewski Michal, Szostakowska Beata, Nahorski Waclaw L, Myjak Przemyslaw, Stanczak Joanna
Department of Tropical Parasitology, Institute of Maritime and Tropical Medicine in Gdynia, Medical University of Gdansk, Poland ; Department of Tropical and Parasitic Diseases, Institute of Maritime and Tropical Medicine in Gdynia, Medical University of Gdansk, Poland.
Department of Infectious Diseases, Medical University of Gdansk, Poland.
Biomed Res Int. 2015;2015:941647. doi: 10.1155/2015/941647. Epub 2015 Sep 16.
Malaria is, along with tuberculosis and HIV/AIDS, one of the three most dangerous infectious diseases in the world. In the absence of native cases since 1963, malaria has remained in Poland an exclusively imported disease, mainly occurring in people travelling to tropical and subtropical areas for professional reasons. The aim of this study was the epidemiological and clinical analysis of 82 patients admitted to the University Center for Maritime and Tropical Medicine (UCMTM), Gdynia, Poland, with a diagnosis of malaria between 2002 and 2014. The "typical" patient with malaria was male, middle-aged, returned from Africa within the preceding 4 weeks, had not used appropriate chemoprophylaxis, and had not applied nonpharmacological methods of prophylaxis, except for window insect screens. P. falciparum was the most frequent species. The most common symptoms included fever, shivers and intensive sweating, thrombocytopenia, elevated creatinine, LDH, D-dimers and CRP, hepatomegaly, and splenomegaly. Within the analyzed group, severe malaria according to WHO standards was diagnosed in 20.7% of patients. Our report presents analysis of the largest series of patients treated for imported malaria in Poland.
疟疾与结核病和艾滋病毒/艾滋病一道,是世界上三种最危险的传染病之一。自1963年波兰本土无疟疾病例以来,疟疾在波兰一直是一种纯粹的输入性疾病,主要发生在因职业原因前往热带和亚热带地区的人群中。本研究的目的是对2002年至2014年期间在波兰格但斯克大学海洋与热带医学中心(UCMTM)收治的82例诊断为疟疾的患者进行流行病学和临床分析。“典型”的疟疾患者为男性,中年,在过去4周内从非洲返回,未使用适当的化学预防措施,除了窗户防虫网外未采取非药物预防方法。恶性疟原虫是最常见的种类。最常见的症状包括发热、寒战和大量出汗、血小板减少、肌酐、乳酸脱氢酶、D-二聚体和C反应蛋白升高、肝肿大和脾肿大。在分析的患者组中,根据世界卫生组织标准诊断为重症疟疾的患者占20.7%。我们的报告对波兰最大系列的输入性疟疾治疗患者进行了分析。