Scott R J, Naidoo J, Lightfoot N F, George R C
Public Health Laboratory, Musgrove Park Hospital, Taunton, Somerset.
Epidemiol Infect. 1989 Feb;102(1):85-91. doi: 10.1017/s095026880002971x.
Erythromycin resistance amongst group A streptococci (GAS) in Great Britain is a relatively rare occurrence and outbreaks have been sporadically reported. Over an 8-month period in 1986 ten associated cases occurred in the town of Bridgewater in Somerset. Isolates were group A, type M4 and resistant to erythromycin (MIC 8 mg/l) but sensitive to lincomycin and clindamycin. Erythromycin resistance was transferable from all isolates to a group A recipient strain. No plasmid DNA could be detected in the original isolates or transconjugants.
在英国，A 组链球菌（GAS）对红霉素耐药的情况相对少见，且仅有零星的暴发报道。1986 年，在萨默塞特郡的布里奇沃特镇，8 个月内出现了 10 例相关病例。分离菌株为 A 组、M4 型，对红霉素耐药（最低抑菌浓度为 8 毫克/升），但对林可霉素和克林霉素敏感。红霉素耐药性可从所有分离菌株转移至 A 组受体菌株。在原始分离菌株或转接合子中均未检测到质粒 DNA。
