Sunde Marie Louise, Øresland Tom, Engebreth Færden Arne
a Department of Colorectal Surgery , Akershus University Hospital , Lørenskog , Norway ;
b Clinic for Surgical Sciences, Faculty of Medicine , University of Oslo, Campus Akershus University Hospital , Lørenskog , Norway.
Scand J Gastroenterol. 2016 Mar;51(3):295-303. doi: 10.3109/00365521.2015.1093165. Epub 2015 Oct 9.
Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the treatment of choice for ulcerative colitis refractory to medical treatment and familial adenomatous polyposis. The objective of this study was to study the impact of postoperative pouch function on sexual function. Sexual function after IPAA surgery has also been compared to sexual function in the average Norwegian population.
All patients having undergone IPAA from 2000 to June 2013 were identified from the hospital medical record files and sent validated questionnaires regarding their sexual function. Pouch function was scored according to Oresland score through a phone interview. Patients operated on or before June 2012 were asked to answer the same questionnaires twice with an interval of one year to see how stable sexual function is over time.
Sixty-eight out of 100 consecutive patients answered the questionnaire regarding both sexual function and pouch function (44 men, 24 women). There was no significant relationship between pouch and sexual function in men (p-value 0.158, corr. coefficient - 0.216). In women there was a significant relationship (p-value - 0.01, corr. coefficient 0.517). There was no significant shift in sexual function during the study period.
We found no significant correlation between sexual function and pouch function in men. In women, we found a significant correlation between poor pouch function and impaired sexual function. As similar studies have found, sexual function remains good after IPAA surgery. This is an important information for patients and physicians, both to inform patients correctly prior to surgery, and in the postoperative follow-up.
回肠储袋肛管吻合术(IPAA)的结直肠修复性切除术是药物治疗无效的溃疡性结肠炎和家族性腺瘤性息肉病的首选治疗方法。本研究的目的是探讨术后储袋功能对性功能的影响。还将IPAA手术后的性功能与挪威普通人群的性功能进行了比较。
从医院病历档案中识别出2000年至2013年6月期间所有接受IPAA手术的患者,并向他们发送关于其性功能的有效问卷。通过电话访谈根据奥雷斯兰评分对储袋功能进行评分。要求在2012年6月或之前接受手术的患者每隔一年两次回答相同的问卷,以观察性功能随时间的稳定性。
100例连续患者中有68例回答了关于性功能和储袋功能的问卷(44例男性,24例女性)。男性储袋功能与性功能之间无显著关系(p值0.158,相关系数 - 0.216)。女性中存在显著关系(p值 - 0.01,相关系数0.517)。在研究期间性功能无显著变化。
我们发现男性性功能与储袋功能之间无显著相关性。在女性中,我们发现储袋功能差与性功能受损之间存在显著相关性。正如类似研究发现的那样,IPAA手术后性功能仍然良好。这对患者和医生来说都是重要信息,既有助于在手术前正确告知患者,也有助于术后随访。