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峡部裂型腰椎滑脱症两种手术治疗的对比研究

[COMPARATIVE STUDY ON TWO SURGICAL TREATMENT OF ISTHMIC SPONDYLOLISTHESIS].

作者信息

Zhang Chao, Sun Tianwei, Tian Rong, Jia Yutao, Xu Tiantong, Shen Qingfeng

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2015 Feb;29(2):179-83.

Abstract

OBJECTIVE

To compare the effectiveness of treatment of isthmic spondylolisthesis between two different fusion surgeries combined with pedicle screw fixation system.

METHODS

A retrospectively analysis was made on the clinical data of 98 patients with lumbar isthmic spondylolisthesis treated between February 2009 and May 2012. Of 98 cases, 53 underwent posterior lumbar interbody fusion (PLIF) combined with internal fixation (group A), and 45 underwent posterolateral fusion (PLF) with internal fixation (group B). There was no significant difference in gender, age, disease duration, segmental lesions, and degree of spondylolisthesis between 2 groups (P > 0.05). The operation time, intraoperative blood loss, reduction rate of spondylolisthesis, reduction loss rate, fusion rate, intervertebral space height, Japanese Orthopedic Association (JOA) score, and the recovery rate of JOA score were compared between 2 groups.

RESULTS

The operation time and intraoperative blood loss of group A were significantly higher than those of group B (P < 0.05). Dural tear occured in 4 cases of group A and 1 case of group B during operation; 6 cases had radicular symptoms after operation in group A; incision infection was found in 1 case of 2 groups respectively. The follow-up time was 24-36 months in group A and was 26-40 months in group B. No significant difference was found in the JOA score at preoperation and 2 weeks after operation between 2 groups (P > 0.05). The JOA score and the recovery rate of JOA score of group A were significantly better than those of group B at 2 years after operation (P < 0.05). X-ray film showed that the reduction rate of group A was significantly higher than that of group B after 2 weeks of operation (P < 0.05); the reduction loss rate of group A was significantly lower than that of group B after 2 years after operation (P < 0.05). The intervertebral space height of group A was significantly higher than that of group B at 2 weeks and 2 years after operation (P<0.05). The fusion rate of group A was significantly better than that of group B at 2 years after operation (P < 0.05).

CONCLUSION

PLIF can achieve a greater degree of reduction, better restore disc height, and lumbar curvature than PLF. PLIF is superior to PLF in maintaining intervertebral height after operation. And PLIF has higher fusion rate, restores the stability of the spine in a greater extent, and it also can achieve a better long-term outcome.

摘要

目的

比较两种不同融合手术联合椎弓根螺钉内固定系统治疗峡部裂型腰椎滑脱症的疗效。

方法

回顾性分析2009年2月至2012年5月间收治的98例峡部裂型腰椎滑脱症患者的临床资料。98例患者中,53例行后路腰椎椎间融合术(PLIF)联合内固定(A组),45例行后外侧融合术(PLF)联合内固定(B组)。两组患者在性别、年龄、病程、节段性病变及腰椎滑脱程度方面差异无统计学意义(P>0.05)。比较两组患者的手术时间、术中出血量、腰椎滑脱复位率、复位丢失率、融合率、椎间隙高度、日本骨科学会(JOA)评分及JOA评分改善率。

结果

A组手术时间及术中出血量均显著高于B组(P<0.05)。A组手术中发生硬膜撕裂4例,B组1例;A组术后有6例出现神经根症状;两组各有1例发生切口感染。A组随访时间为2436个月,B组为2640个月。两组术前及术后2周JOA评分差异无统计学意义(P>0.05)。术后2年,A组JOA评分及JOA评分改善率均显著优于B组(P<0.05)。X线片显示,术后2周A组腰椎滑脱复位率显著高于B组(P<0.05);术后2年A组复位丢失率显著低于B组(P<0.05)。术后2周及2年时A组椎间隙高度均显著高于B组(P<0.05)。术后2年A组融合率显著优于B组(P<0.05)。

结论

与PLF相比,PLIF能达到更大程度的复位,更好地恢复椎间盘高度及腰椎曲度。PLIF在术后维持椎间隙高度方面优于PLF。且PLIF融合率更高,能更大程度恢复脊柱稳定性,远期疗效更佳。

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