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综合癌症中心姑息治疗人群的分类

Classification of a palliative care population in a comprehensive cancer centre.

作者信息

Benthien Kirstine Skov, Nordly Mie, Videbæk Katja, Kurita Geana Paula, von der Maase Hans, Timm Helle, Simonsen Mette Kildevæld, Johansen Christoffer, Sjøgren Per

机构信息

Department of Oncology, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Faculty of Health and Medical Sciences, Copenhagen University, Blegdamsvej 3B, 2000, Copenhagen, Denmark.

出版信息

Support Care Cancer. 2016 Apr;24(4):1865-73. doi: 10.1007/s00520-015-2979-z. Epub 2015 Oct 13.

Abstract

PURPOSE

The purposes of the present study were to classify the palliative care population (PCP) in a comprehensive cancer centre by using information on antineoplastic treatment options and to analyse associations between socio-demographic factors, cancer diagnoses, treatment characteristics and receiving specialist palliative care (SPC).

METHODS

This is a cross-sectional screening study of patients with cancer in the Department of Oncology, Rigshospitalet, Copenhagen University Hospital for 6 months. Patients were assessed to be included in the DOMUS study: a randomised controlled trial of accelerated transition to SPC at home (NCT01885637). The PCP was classified as patients with incurable cancer and limited or no antineoplastic treatment options. Patients with performance status 2-4 were further classified as the essential palliative care population (EPCP).

RESULTS

During the study period, 3717 patients with cancer were assessed. The PCP comprised 513 patients yielding a prevalence of 14 %. The EPCP comprised 256 patients (7 %). The EPCP was older, more likely inpatients, had a higher comorbidity burden and 38 % received SPC. Women, patients without caregivers and patients with breast cancer were more likely to receive SPC.

CONCLUSIONS

By using objective criteria from clinical data and systematic screening, the observed prevalence of the PCP of 14 % may be generalisable to comprehensive cancer centres with similar composition of cancer diagnoses.

摘要

目的

本研究旨在利用抗肿瘤治疗方案的信息,对一家综合癌症中心的姑息治疗人群(PCP)进行分类,并分析社会人口学因素、癌症诊断、治疗特征与接受专科姑息治疗(SPC)之间的关联。

方法

这是一项对哥本哈根大学医院里格霍斯皮塔尔肿瘤学系的癌症患者进行的为期6个月的横断面筛查研究。患者被评估纳入DOMUS研究:一项关于在家中加速过渡到SPC的随机对照试验(NCT01885637)。PCP被分类为患有无法治愈的癌症且抗肿瘤治疗选择有限或没有的患者。体能状态为2 - 4的患者进一步被分类为基本姑息治疗人群(EPCP)。

结果

在研究期间,评估了3717例癌症患者。PCP包括513例患者,患病率为14%。EPCP包括256例患者(7%)。EPCP年龄更大,更有可能是住院患者,合并症负担更高,38%接受了SPC。女性、没有照顾者的患者和乳腺癌患者更有可能接受SPC。

结论

通过使用临床数据中的客观标准和系统筛查,观察到的PCP患病率14%可能适用于具有类似癌症诊断构成的综合癌症中心。

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