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腹主动脉瘤修复术后术后发病率调查的有效性-一项前瞻性观察研究。

Validity of the Postoperative Morbidity Survey after abdominal aortic aneurysm repair-a prospective observational study.

机构信息

Department of Perioperative Care, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Health and Social Care Institute, Teesside University, Middlesbrough, UK.

出版信息

Perioper Med (Lond). 2015 Oct 12;4:10. doi: 10.1186/s13741-015-0020-1. eCollection 2015.

Abstract

BACKGROUND

Currently, there is no standardised tool used to capture morbidity following abdominal aortic aneurysm (AAA) repair. The aim of this prospective observational study was to validate the Postoperative Morbidity Survey (POMS) according to its two guiding principles: to only capture morbidity substantial enough to delay discharge from hospital and to be a rapid, simple screening tool.

METHODS

A total of 64 adult patients undergoing elective infrarenal AAA repair participated in the study. Following surgery, the POMS was recorded daily, by trained research staff with the clinical teams blinded, until hospital discharge or death. We modelled the data using Cox regression, accounting for the competing risk of death, with POMS as a binary time-dependent (repeated measures) internal covariate. For each day for each patient, 'discharged' (yes/no) was the event, with the elapsed number of days post-surgery as the time variable. We derived the hazard ratio for any POMS morbidity (score 1-9) vs. no morbidity (zero), adjusted for type of repair (endovascular versus open), age and aneurysm size.

RESULTS

The hazard ratio for alive discharge with any POMS-recorded morbidity versus no morbidity was 0.130 (95 % confidence interval 0.070 to 0.243). The median time-to-discharge was 13 days after recording any POMS morbidity vs. 2 days after scoring zero for POMS morbidity. Compliance with POMS completion was 99.5 %.

CONCLUSIONS

The POMS is a valid tool for capturing short-term postoperative morbidity following elective infrarenal AAA repair that is substantial enough to delay discharge from hospital. Daily POMS measurement is recommended to fully capture morbidity and allow robust analysis. The survey could be a valuable outcome measure for use in quality improvement programmes and future research.

摘要

背景

目前,尚无用于捕获腹主动脉瘤(AAA)修复后发病率的标准化工具。本前瞻性观察研究的目的是根据其两个指导原则验证术后发病率调查(POMS):仅捕获足以延迟出院的发病率;并作为一种快速、简单的筛查工具。

方法

共有 64 名接受择期肾下 AAA 修复的成年患者参与了这项研究。手术后,由经过培训的研究人员每天记录 POMS,临床团队对此不知情,直到患者出院或死亡。我们使用 Cox 回归对数据进行建模,考虑到死亡的竞争风险,将 POMS 作为二进制时间依赖性(重复测量)内部协变量。对于每位患者的每一天,“出院”(是/否)是事件,手术后天数是时间变量。我们为任何 POMS 发病率(评分 1-9)与无发病率(零)推导了风险比,调整了修复类型(血管内与开放)、年龄和动脉瘤大小。

结果

与无 POMS 记录发病率相比,任何 POMS 记录发病率与存活出院的风险比为 0.130(95%置信区间 0.070 至 0.243)。记录任何 POMS 发病率后的中位出院时间为 13 天,而 POMS 发病率为零时为 2 天。完成 POMS 调查的依从性为 99.5%。

结论

POMS 是一种有效的工具,可用于捕获择期肾下 AAA 修复后的短期术后发病率,足以延迟出院。建议每天进行 POMS 测量,以充分捕获发病率并进行稳健分析。该调查可能是质量改进计划和未来研究中有用的结果衡量标准。

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