Nowak D, Wiebicke W, Magnussen H
Krankenhaus Grosshansdorf, Zentrum für Pneumologie und Thoraxchirurgie, LVA Freie und Hansestadt Hamburg.
Monatsschr Kinderheilkd. 1989 Jan;137(1):8-12.
The prevalence of childhood asthma is about 10% as compared to 6% in adults. 40% to 80% of asthmatic children become symptom-free during adolescence, but asymptomatic bronchial hyperreactivity may persist. About one third of those patients who have become symptom-free during adolescence will have relapses in adult life. Some factors seem to predict a worse prognosis of the disease: positive family history, concomitant allergic diseases, eczema, severe symptoms at the onset of the disease and during adolescence, a high degree of non-specific bronchial hyperreactivity, active and passive smoking. Questionable prognostic factors include sex, age of onset and breast-feeding.
儿童哮喘的患病率约为10%,而成人哮喘的患病率为6%。40%至80%的哮喘儿童在青春期症状消失,但无症状的支气管高反应性可能会持续存在。在青春期症状消失的患者中,约三分之一在成年后会复发。一些因素似乎预示着疾病的预后较差:阳性家族史、合并过敏性疾病、湿疹、疾病发作时及青春期出现的严重症状、高度的非特异性支气管高反应性、主动和被动吸烟。存在疑问的预后因素包括性别、发病年龄和母乳喂养。