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比较HIV检测策略的成本效益:华盛顿特区的针对性检测和常规检测

Comparing Cost-Effectiveness of HIV Testing Strategies: Targeted and Routine Testing in Washington, DC.

作者信息

Castel Amanda D, Choi Sungwoog, Dor Avi, Skillicorn Jennifer, Peterson James, Rocha Nestor, Kharfen Michael

机构信息

The Milken Institute School of Public Health at the George Washington University, Washington, DC, United States of America.

The George Washington University School of Public Policy and Public Administration, Washington, DC, United States of America.

出版信息

PLoS One. 2015 Oct 14;10(10):e0139605. doi: 10.1371/journal.pone.0139605. eCollection 2015.

Abstract

BACKGROUND

Routine HIV testing is an essential approach to identifying undiagnosed infections, linking people to care and treatment, and preventing new infections. In Washington, DC, where HIV prevalence is 2.4%, a combination of routine and targeted testing approaches has been implemented since 2006.

METHODS

We sought to evaluate the cost effectiveness of the District of Columbia (DC) Department of Health's routine and targeted HIV testing implementation strategies. We collected HIV testing data from 3 types of DC Department of Health-funded testing sites (clinics, hospitals, and community-based organizations); collected testing and labor costs; and calculated effectiveness measures including cost per new diagnosis and cost per averted transmission.

RESULTS

Compared to routine testing, targeted testing resulted in higher positivity rates (1.33% vs. 0.44%). Routine testing averted 34.30 transmissions per year compared to targeted testing at 17.78. The cost per new diagnosis was lower for targeted testing ($2,467 vs. $7,753 per new diagnosis) as was the cost per transmission averted ($33,160 vs. $104,205). When stratified by testing site, both testing approaches were most cost effective in averting new transmissions when conducted by community based organizations ($25,037 routine; $33,123 targeted) compared to hospitals or clinics.

CONCLUSIONS

While routine testing identified more newly diagnosed infections and averted more infections than targeted testing, targeted testing is more cost effective per diagnosis and per transmission averted overall. Given the high HIV prevalence in DC, the DC Department of Health's implementation strategy should continue to encourage routine testing implementation with emphasis on a combined testing strategy among community-based organizations.

摘要

背景

常规艾滋病毒检测是识别未诊断感染、帮助人们获得护理和治疗以及预防新感染的重要方法。在华盛顿特区,艾滋病毒流行率为2.4%,自2006年以来已实施了常规检测和针对性检测相结合的方法。

方法

我们试图评估哥伦比亚特区(DC)卫生部常规和针对性艾滋病毒检测实施策略的成本效益。我们从DC卫生部资助的3种检测地点(诊所、医院和社区组织)收集了艾滋病毒检测数据;收集了检测和劳动力成本;并计算了有效性指标,包括每例新诊断的成本和每避免一次传播的成本。

结果

与常规检测相比,针对性检测的阳性率更高(1.33%对0.44%)。与针对性检测每年避免17.78次传播相比,常规检测每年避免34.30次传播。针对性检测每例新诊断的成本较低(每例新诊断2467美元对7753美元),每避免一次传播的成本也较低(33160美元对104205美元)。按检测地点分层时,与医院或诊所相比,两种检测方法在由社区组织进行检测时避免新传播方面最具成本效益(常规检测25037美元;针对性检测33123美元)。

结论

虽然常规检测比针对性检测发现了更多新诊断的感染并避免了更多感染,但针对性检测在每次诊断和总体避免每次传播方面更具成本效益。鉴于DC的艾滋病毒高流行率,DC卫生部实施策略应继续鼓励实施常规检测,重点是社区组织中的联合检测策略。

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