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利用艾滋病病毒护理连续统一体结果来确定进行针对性艾滋病病毒检测的地理区域的可行性。

Feasibility of Using HIV Care-Continuum Outcomes to Identify Geographic Areas for Targeted HIV Testing.

作者信息

Castel Amanda D, Kuo Irene, Mikre Meriam, Young Toni, Haddix Meredith, Das Suparna, Maugham Geoffrey, Reisen Carol

机构信息

*Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, Washington, DC; †Community Education Group, Washington, DC; and ‡District of Columbia Department of Health, HIV/AIDS, Hepatitis, STD, TB Administration, Washington, DC.

出版信息

J Acquir Immune Defic Syndr. 2017 Feb 1;74 Suppl 2(Suppl 2):S96-S103. doi: 10.1097/QAI.0000000000001238.

Abstract

BACKGROUND

Improved detection and linkage to care of previously undiagnosed HIV infections require innovative approaches to testing. We sought to determine the feasibility of targeted HIV testing in geographic areas, defined by continuum of care parameters, to identify HIV-infected persons needing linkage or engagement in care.

METHODS

Using HIV surveillance data from Washington, DC, we identified census tracts that had an HIV prevalence >1% and were either above (higher risk areas-HRAs) or below (lower risk areas-LRAs) the median for 3 indicators: monitored viral load, proportion of persons out of care (OOC), and never in care. Community-based HIV rapid testing and participant surveys were conducted in the 20 census tracts meeting the criteria. Areas were mapped using ArcGIS, and descriptive and univariate analyses were conducted comparing the areas and participants.

RESULTS

Among 1471 persons tested, 28 (1.9%) tested HIV positive; 2.1% in HRAs vs. 1.7% in LRAs (P = 0.57). Higher proportions of men (63.7% vs. 56.7%, P = 0.007) and fewer blacks (91.0% vs. 94.6%, P = 0.008) were tested in LRAs vs. HRAs; no differences were observed in risk behaviors between the areas. Among HIV-positive participants, 54% were new diagnoses (n = 9) or OOC (n = 6), all were Black, 64% were men with a median age of 51 years.

CONCLUSIONS

Although significant differences in HIV seropositivity were not observed between testing areas, our approach proved feasible and enabled identification of new diagnoses and OOC HIV-infected persons. This testing paradigm could be adapted in other locales to identify areas for targeted HIV testing and other reengagement efforts.

摘要

背景

改善对先前未诊断出的艾滋病毒感染的检测并与护理建立联系需要创新的检测方法。我们试图确定在由护理连续参数定义的地理区域进行有针对性的艾滋病毒检测的可行性,以识别需要与护理建立联系或参与护理的艾滋病毒感染者。

方法

利用来自华盛顿特区的艾滋病毒监测数据,我们确定了艾滋病毒患病率>1%且在三个指标中位数之上(高风险区域-HRAs)或之下(低风险区域-LRAs)的普查区:监测的病毒载量、失访(OOC)人员比例和从未接受护理的人员比例。在符合标准的20个普查区开展了基于社区的艾滋病毒快速检测和参与者调查。使用ArcGIS对区域进行绘图,并进行描述性和单变量分析以比较这些区域和参与者。

结果

在1471名接受检测的人员中,28人(1.9%)艾滋病毒检测呈阳性;高风险区域为2.1%,低风险区域为1.7%(P = 0.57)。与高风险区域相比,低风险区域接受检测的男性比例更高(63.7%对56.7%,P = 0.007),黑人比例更低(91.0%对94.6%,P = 0.008);两个区域在风险行为方面未观察到差异。在艾滋病毒检测呈阳性的参与者中,54%为新诊断病例(n = 9)或失访者(n = 6),均为黑人,64%为男性,中位年龄为51岁。

结论

尽管在检测区域之间未观察到艾滋病毒血清阳性率的显著差异,但我们的方法被证明是可行的,并且能够识别出新诊断病例和失访的艾滋病毒感染者。这种检测模式可在其他地区进行调整,以确定有针对性的艾滋病毒检测和其他重新参与护理工作的区域。

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