肺癌的双能计算机断层扫描虚拟单能量成像：最佳能量水平评估

Dual-Energy Computed Tomography Virtual Monoenergetic Imaging of Lung Cancer: Assessment of Optimal Energy Levels.

作者信息

Kaup Moritz, Scholtz Jan-Erik, Engler Alexander, Albrecht Moritz H, Bauer Ralf W, Kerl J Matthias, Beeres Martin, Lehnert Thomas, Vogl Thomas J, Wichmann Julian L

机构信息

From the Departments of *Diagnostic and Interventional Radiology and †Cranio-Maxillofacial and Plastic Facial Surgery, University Hospital Frankfurt, Frankfurt, Germany.

出版信息

J Comput Assist Tomogr. 2016 Jan-Feb;40(1):80-5. doi: 10.1097/RCT.0000000000000319.

DOI:10.1097/RCT.0000000000000319

PMID:26466115

Abstract

OBJECTIVE

The aim of the study was to evaluate objective and subjective image qualities of virtual monoenergetic imaging (VMI) in dual-source dual-energy computed tomography (DECT) and optimal kiloelectron-volt (keV) levels for lung cancer.

METHODS

Fifty-nine lung cancer patients underwent chest DECT. Images were reconstructed as VMI series at energy levels of 40, 60, 80, and 100 keV and standard linear blending (M_0.3) for comparison. Objective and subjective image qualities were assessed.

RESULTS

Lesion contrast peaked in 40-keV VMI reconstructions (2.5 ± 2.9) and 60 keV (1.9 ± 3.0), which was superior to M_0.3 (0.5 ± 2.7) for both comparisons (P < 0.001). Compared with M_0.3, subjective ratings were highest for 60-keV VMI series regarding general image quality (4.48 vs 4.52; P = 0.74) and increased for lesion demarcation (4.07 vs 4.84; P < 0.001), superior to all other VMI series (P < 0.001). Image sharpness was similar between both series. Image noise was rated superior in the 80-keV and M_0.3 series, followed by 60 keV.

CONCLUSIONS

Virtual monoenergetic imaging reconstructions at 60-keV provided the best combination of subjective and objective image qualities in DECT of lung cancer.

摘要

目的

本研究旨在评估双源双能量计算机断层扫描（DECT）中虚拟单能量成像（VMI）的客观和主观图像质量，以及肺癌的最佳千电子伏特（keV）水平。

方法

59例肺癌患者接受胸部DECT检查。图像被重建为40、60、80和100 keV能量水平的VMI系列以及标准线性融合（M_0.3）用于比较。评估客观和主观图像质量。

结果

在40 keV的VMI重建（2.5±2.9）和60 keV（1.9±3.0）中病变对比度达到峰值，在这两种比较中均优于M_0.3（0.5±2.7）（P<0.001）。与M_0.3相比，60 keV的VMI系列在总体图像质量方面主观评分最高（4.48对4.52；P = 0.74），在病变边界划分方面评分增加（4.07对4.84；P<0.001），优于所有其他VMI系列（P<0.001）。两个系列的图像清晰度相似。80 keV和M_0.3系列的图像噪声评分更高，其次是60 keV。