Ma Chunming, Liu Yue, Lu Qiang, Lu Na, Liu Xiaoli, Tian Yiming, Wang Rui, Yin Fuzai
Department of Endocrinology, The First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei Province, China.
Blood Press Monit. 2016 Feb;21(1):43-8. doi: 10.1097/MBP.0000000000000159.
The blood pressure-to-height ratio (BPHR) has been shown to be an accurate index for screening hypertension in children and adolescents.
The aim of the present study was to perform a meta-analysis to assess the performance of BPHR for the assessment of hypertension.
Electronic and manual searches were performed to identify studies of the BPHR. After methodological quality assessment and data extraction, pooled estimates of the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio, area under the receiver operating characteristic curve and summary receiver operating characteristics were assessed systematically. The extent of heterogeneity for it was assessed.
Six studies were identified for analysis. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio values of BPHR, for assessment of hypertension, were 96% [95% confidence interval (CI)=0.95-0.97], 90% (95% CI=0.90-0.91), 10.68 (95% CI=8.03-14.21), 0.04 (95% CI=0.03-0.07) and 247.82 (95% CI=114.50-536.34), respectively. The area under the receiver operating characteristic curve was 0.9472.
The BPHR had higher diagnostic accuracies for identifying hypertension in children and adolescents.
血压与身高比值(BPHR)已被证明是筛查儿童和青少年高血压的准确指标。
本研究的目的是进行一项荟萃分析,以评估BPHR用于评估高血压的性能。
通过电子和手动检索来识别关于BPHR的研究。在进行方法学质量评估和数据提取后,系统地评估了敏感性、特异性、阳性似然比、阴性似然比、诊断比值比、受试者工作特征曲线下面积和汇总受试者工作特征的合并估计值。评估了其异质性程度。
确定了六项研究进行分析。BPHR用于评估高血压的合并敏感性、特异性、阳性似然比、阴性似然比和诊断比值比分别为96%[95%置信区间(CI)=0.95 - 0.97]、90%(95%CI = 0.90 - 0.91)、10.68(95%CI = 8.03 - 14.21)、0.04(95%CI = 0.03 - 0.07)和247.82(95%CI = 114.50 - 536.34)。受试者工作特征曲线下面积为0.9472。
BPHR在识别儿童和青少年高血压方面具有较高的诊断准确性。