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2例婴儿的小儿播散性勒米埃尔综合征:古老疾病面前年龄不是问题

Pediatric Disseminated Lemierre Syndrome in 2 Infants: Not Too Young for an Ancient Disease.

作者信息

García-Salido Alberto, Unzueta-Roch José Luis, García-Teresa María Ángeles, Sirvent-Cerdá Sara, Martínez de Azagra-Garde Amelia, Casado-Flores Juan

机构信息

From the Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

出版信息

Pediatr Emerg Care. 2017 Jul;33(7):490-493. doi: 10.1097/PEC.0000000000000570.

Abstract

The Lemierre syndrome is characterized by an oropharyngeal infection, thrombosis of the internal jugular vein, and multiple septic metastases. Fusobacterium necrophorum is a common cause of it. The incidence is 0.6 to 2.3 cases per million with a mortality rate of 4% to 18%. Its fast evolution and the possibility of severe complications require a high index of suspicion for its diagnosis. We present 2 infants with Lemierre syndrome. The younger case, a 6-month-old infant, was fully recovered. In the other side, and despite an aggressive therapy, an 18-month-old infant developed cerebral palsy. We also provide a short literature review with a focus on clinical presentation and differential diagnosis in order to initiate an early and adequate therapy.

摘要

勒米尔综合征的特征为口咽感染、颈内静脉血栓形成及多发性脓毒性转移。坏死梭杆菌是其常见病因。发病率为每百万人口中有0.6至2.3例,死亡率为4%至18%。其病情进展迅速且有发生严重并发症的可能,因此诊断时需要高度怀疑。我们报告2例勒米尔综合征患儿。年龄较小的病例为一名6个月大的婴儿,已完全康复。另一方面,尽管进行了积极治疗,一名18个月大的婴儿仍发展为脑瘫。我们还提供了一篇简短的文献综述,重点关注临床表现和鉴别诊断,以便启动早期且充分的治疗。

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