Zelinkova Zuzana, Wenzl Thomas
a European Commission, Joint Research Centre , Institute for Reference Materials and Measurements, Standards for Food Bioscience Unit , Geel , Belgium.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(11):1914-26. doi: 10.1080/19440049.2015.1087059. Epub 2015 Oct 14.
Several food supplements comprising botanical, oil and bee products collected from retail markets in different countries were tested for the occurrence of 4 EU marker Polycyclic aromatic hydrocarbons (PAHs; benz[a]anthracene, chrysene, benzo[b]fluoranthene and benzo[a]pyrene). A robust GC/MS-based stable-isotope dilution method was used taking into account the differences in the type of matrices. The accuracy of the results was assessed by implementing several quality control tools. Sixty-eight samples of 94 analysed products exceeded the level of 0.5 μg/kg for the sum of the four EU marker PAHs (ΣPAH4). Benzo[a]pyrene exceeded the limit of quantification in 49 samples. The PAH with the highest abundance in all products was chrysene. On average, propolis extracts and other bee products showed relatively high levels of ΣPAH4 (mean 188.2 μg/kg), whereas the contamination levels of fish oil supplements were very low or mostly undetectable. Considerably high ΣPAH4 amounts found in some samples could remarkably increase the daily exposure of consumers to PAHs, demonstrating the need for continuous monitoring of ΣPAH4 in food supplements.
对从不同国家零售市场收集的几种包含植物、油类和蜂产品的食品补充剂进行了检测，以确定4种欧盟标记多环芳烃（PAHs；苯并[a]蒽、屈、苯并[b]荧蒽和苯并[a]芘）的存在情况。考虑到基质类型的差异，使用了一种基于气相色谱/质谱的稳健稳定同位素稀释方法。通过实施多种质量控制工具来评估结果的准确性。在分析的94种产品中，有68个样品的4种欧盟标记PAHs总和（ΣPAH4）超过了0.5 μg/kg的水平。苯并[a]芘在49个样品中超过了定量限。所有产品中含量最高的PAH是屈。平均而言，蜂胶提取物和其他蜂产品的ΣPAH4水平相对较高（平均188.2 μg/kg），而鱼油补充剂的污染水平非常低或大多无法检测到。在一些样品中发现的相当高的ΣPAH4含量可能会显著增加消费者对PAHs的每日暴露量，这表明需要持续监测食品补充剂中的ΣPAH4。
