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一项针对中国南方人群眼部疾病的基于人群的研究的设计与基线特征:东莞眼病研究。

Design and baseline characteristics of a population-based study of eye disease in southern Chinese people: the Dongguan Eye Study.

作者信息

Meng Qianli, Cui Ying, Zhang Min, Zhang Lixin, Zhang Liang, Zhang Jinxin, Kuang Jian, Liu Qingyang, Zheng Yang, Luo Zhongling, Liu Huikun, Zhu Guoping, Cai Jingjing, Zhang Guanrong, Wen Xingxuan, Guo Haike

机构信息

Guangdong Eye Institute, Department of Ophthalmology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.

Department of Ophthalmology, Dongguan People's Hospital, Dongguan, Guangdong, China.

出版信息

Clin Exp Ophthalmol. 2016 Apr;44(3):170-80. doi: 10.1111/ceo.12670. Epub 2016 Feb 5.

DOI:10.1111/ceo.12670
PMID:26468890
Abstract

BACKGROUND

To describe the study design, methodology and baseline characteristics of the Dongguan Eye Study.

DESIGN

Population-based, cross-sectional study

PARTICIPANTS

A total of 8952 rural-dwelling residents aged 40 years or older in Hengli, Dongguan.

METHODS

The Dongguan Eye Study was conducted from September 2011 to February 2012. The interview covered demographic data, socio-economic status and health- and vision-related quality of life. Physical measurements included height, weight, waist and hip circumference, heart rate and blood pressure. Laboratory tests included fasting blood glucose, haemoglobin A1c, oral glucose tolerance, serum total cholesterol, triglycerides, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, serum creatinine, blood urea nitrogen and uric acid. Ophthalmic examinations included visual acuity and autorefraction testing, intraocular pressure measurement, slit-lamp examination, ocular biometry, gonioscopy, fundus photography, retinal nerve fibre layer imaging and visual field testing.

MAIN OUTCOME MEASURES

Prevalence and risk factors for visual impairment, blindness, eye diseases and their associations with systemic medical indicators or health-related lifestyles, as well as epidemiological data on diabetic subjects. Methodology, response rates and baseline characteristics are presented.

RESULTS

Of the 11 357 individuals eligible for the Dongguan Eye Study, 8952 (78.82%) subjects participated. All participants were self-identified Han Chinese. The average age was 54.0 years, 59.9% were female, 48.4% were farmers and 77.2% had elementary or junior middle school educational levels. The average body mass index and waist-hip ratio were 24.6 ± 3.9 kg/m(2) and 0.9 ± 0.2.

CONCLUSIONS

Data from the Dongguan Eye Study provide information concerning the prevalence, risk factors and impacts of eye diseases in rural residents undergoing urbanization in southern China.

摘要

背景

描述东莞眼病研究的研究设计、方法及基线特征。

设计

基于人群的横断面研究

参与者

东莞横沥镇共8952名40岁及以上的农村居民。

方法

东莞眼病研究于2011年9月至2012年2月进行。访谈涵盖人口统计学数据、社会经济状况以及与健康和视力相关的生活质量。体格测量包括身高、体重、腰围和臀围、心率及血压。实验室检查包括空腹血糖、糖化血红蛋白、口服葡萄糖耐量、血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、血清肌酐、血尿素氮及尿酸。眼科检查包括视力和自动验光测试、眼压测量、裂隙灯检查、眼部生物测量、前房角镜检查、眼底照相、视网膜神经纤维层成像及视野测试。

主要观察指标

视力损害、失明、眼病的患病率及危险因素,及其与全身医学指标或健康相关生活方式的关联,以及糖尿病患者的流行病学数据。呈现方法、应答率及基线特征。

结果

在11357名符合东莞眼病研究条件的个体中,8952名(78.82%)受试者参与。所有参与者均自称汉族。平均年龄为54.0岁,59.9%为女性,48.4%为农民,77.2%具有小学或初中学历。平均体重指数和腰臀比分别为24.6±3.9kg/m²和0.9±0.2。

结论

东莞眼病研究的数据提供了有关中国南方正在经历城市化的农村居民眼病患病率、危险因素及影响的信息。

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