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2 型糖尿病患者中低视力和盲的患病率及其病因:东莞眼病研究。

Prevalence and causes of low vision and blindness in a Chinese population with type 2 diabetes: the Dongguan Eye Study.

机构信息

Guangdong Eye Institute, Department of Ophthalmology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.

Department of Ophthalmology, Dongguan People's Hospital, Dongguan, Guangdong, China.

出版信息

Sci Rep. 2017 Sep 11;7(1):11195. doi: 10.1038/s41598-017-11365-z.

Abstract

To assess the prevalence and causes of low vision and blindness in type 2 diabetes patients, a population-based cross-sectional study including 8952 rural-dwelling residents aged 40 years or older from Hengli Town in Southern China was conducted. Participants underwent standard interviews, physical measurements, laboratory tests, and comprehensive eye examinations. Low vision and blindness were defined based on WHO criteria. Visual acuity data were available for 1348 (89.9%) of the 1500 subjects with type 2 diabetes. Age-standardized prevalence of bilateral low vision and blindness assessed in the better-seeing eye was 2.9% (95% confidence interval [CI]: 2.0-3.8) and 0.7% (95% CI: 0.2-1.1) based on best-corrected visual acuity (BCVA). Cataracts were the primary cause of low vision and blindness. Visual impairment was associated with age (odds ratio [OR]: 3.73, 95% CI: 2.39-5.83), education level (OR: 3.21, 95% CI: 1.63-6.29), duration of diabetes (OR: 1.14, 95% CI: 1.04-1.25) and body mass index (OR: 0.86, 95% CI: 0.77-0.95). Our data suggest that approximately 70% of visual impairment in this diabetic population could be eliminated with appropriate cataract surgery or spectacle correction. Greater consideration should be given to older type 2 diabetes patients with a level of lower education.

摘要

为了评估 2 型糖尿病患者低视力和失明的患病率和病因,在中国南方横沥镇进行了一项基于人群的横断面研究,共纳入 8952 名年龄在 40 岁及以上的农村居民。参与者接受了标准的访谈、身体测量、实验室检查和全面的眼部检查。低视力和失明根据世界卫生组织(WHO)的标准定义。共有 1348 名(89.9%)2 型糖尿病患者的视力数据可用。在较好眼,经年龄标准化后双侧低视力和失明的患病率分别为 2.9%(95%置信区间[CI]:2.0-3.8)和 0.7%(95% CI:0.2-1.1),基于最佳矫正视力(BCVA)。白内障是低视力和失明的主要原因。视力损害与年龄(比值比[OR]:3.73,95% CI:2.39-5.83)、教育程度(OR:3.21,95% CI:1.63-6.29)、糖尿病病程(OR:1.14,95% CI:1.04-1.25)和身体质量指数(OR:0.86,95% CI:0.77-0.95)有关。我们的数据表明,通过适当的白内障手术或眼镜矫正,该糖尿病患者人群中约 70%的视力损害是可以消除的。应更多地考虑受教育程度较低的老年 2 型糖尿病患者。

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