Varma Rohit, Hsu Chunyi, Wang Dandan, Torres Mina, Azen Stanley P
Illinois Eye and Ear Infirmary, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago , Chicago, IL , USA and.
Ophthalmic Epidemiol. 2013 Dec;20(6):335-47. doi: 10.3109/09286586.2013.823505. Epub 2013 Sep 18.
To summarize the study design, operational strategies and procedures of the Chinese American Eye Study (CHES), a population-based assessment of the prevalence of visual impairment, ocular disease, and visual functioning in Chinese Americans.
This population-based, cross-sectional study included 4570 Chinese participants aged 50 years and older, residing in the city of Monterey Park, California. Each eligible participant completed a detailed interview and eye examination. The interview included an assessment of demographic, behavioral and ocular risk factors and health-related and vision-related quality of life. The eye examination included measurements of visual acuity, intraocular pressure, visual fields, fundus and optic disc photography, a detailed anterior and posterior segment examination, and measurements of blood pressure, glycosylated hemoglobin levels, and blood glucose levels.
The objectives of the CHES are to obtain prevalence estimates of visual impairment, refractive error, diabetic retinopathy, open-angle and angle-closure glaucoma, lens opacities, and age-related macular degeneration in Chinese Americans. In addition, outcomes include effect estimates for risk factors associated with eye diseases. Lastly, CHES will investigate the genetic determinants of myopia and glaucoma.
The CHES will provide information about the prevalence and risk factors of ocular diseases in one of the fastest growing minority groups in the United States.
总结华裔美国人眼病研究(CHES)的研究设计、操作策略及程序,该研究是一项基于人群的关于华裔美国人视力损害、眼病及视觉功能患病率的评估。
这项基于人群的横断面研究纳入了4570名年龄在50岁及以上、居住在加利福尼亚州蒙特雷帕克市的华裔参与者。每位符合条件的参与者均完成了详细的访谈及眼部检查。访谈内容包括对人口统计学、行为及眼部危险因素以及与健康和视力相关的生活质量的评估。眼部检查包括视力测量、眼压测量、视野检查、眼底及视盘摄影、详细的眼前段和眼后段检查,以及血压、糖化血红蛋白水平和血糖水平的测量。
CHES的目标是获取华裔美国人视力损害、屈光不正、糖尿病视网膜病变、开角型和闭角型青光眼、晶状体混浊及年龄相关性黄斑变性的患病率估计值。此外,研究结果还包括与眼病相关的危险因素的效应估计值。最后,CHES将研究近视和青光眼的遗传决定因素。
CHES将为美国增长最快的少数族裔群体之一的眼病患病率及危险因素提供信息。