MMWR Morb Mortal Wkly Rep. 2015 Oct 16;64(40):1147-9. doi: 10.15585/mmwr.mm6440a5.
What is already known on this topic? Human papillomavirus (HPV) infection is common and aggressive in persons infected with human immunodeficiency virus (HIV). With an HIV prevalence of 28% among females aged 15–49, cervical cancer is the leading cause of cancer death among women in Botswana. Before 2013, HPV vaccine had not been used in the public sector in Botswana.What is added by this report? Efforts to expand services for cervical cancer through the Pink Ribbon Red Ribbon initiative focused on HPV-related disease in Botswana. A demonstration project for HPV vaccination was developed by the Ministry of Health for school girls aged ≥9 years in primary schools in one community. A total of 1,967 (79%) of 2,488 eligible girls received 3 doses of vaccine in the immunization effort that was centered in schools.What are the implications for public health practice? Preventing HPV infection in girls is an important component of a national comprehensive cervical cancer control program. HPV vaccination programming is challenging, and demonstration projects can prepare countries for national introduction. The success of the initial HPV vaccination effort in Botswana led to an expanded project in 2014, with implementation of nationwide rollout of the HPV vaccine in 2015. It might be beneficial for future HPV vaccination campaigns to include strategies to reach out-of-school girls.
在这个话题上已知的是什么?人乳头瘤病毒(HPV)感染在感染人类免疫缺陷病毒(HIV)的人中很常见且具有侵袭性。由于 15-49 岁女性中 HIV 的流行率为 28%,宫颈癌是博茨瓦纳女性癌症死亡的主要原因。在 2013 年之前,HPV 疫苗尚未在博茨瓦纳公共部门使用。
本报告增加了什么?通过粉红丝带红丝带倡议,努力扩大宫颈癌服务范围,重点关注博茨瓦纳与 HPV 相关的疾病。卫生部为一个社区的小学 9 岁及以上的女学生制定了 HPV 疫苗接种示范项目。在以学校为中心的免疫接种工作中,共有 2488 名符合条件的女孩中的 1967 名(79%)接种了 3 剂疫苗。
这对公共卫生实践有什么影响?在女孩中预防 HPV 感染是国家综合宫颈癌控制计划的重要组成部分。HPV 疫苗接种规划具有挑战性,示范项目可以为国家引入做好准备。博茨瓦纳最初 HPV 疫苗接种工作的成功导致 2014 年扩大了项目,并于 2015 年在全国范围内推出 HPV 疫苗。未来的 HPV 疫苗接种运动可能会受益于制定接触校外女孩的策略。