Novais Eduardo Amorim, Badaró Emmerson, Allemann Norma, Morales Maira Saad Ávila, Rodrigues Eduardo Büchele, de Souza Lima Rodrigo, Regatieri Caio Vinicius Saito, Belfort Rubens
Ophthalmic Surg Lasers Imaging Retina. 2015 Oct;46(9):920-4. doi: 10.3928/23258160-20151008-04.
To study the correlation between the choroidal thickness (CT) measured by spectral-domain optical coherence tomography (SD-OCT) and retrobulbar blood flow measured by color Doppler flowmetry (CD) in normal subjects.
Healthy subjects underwent enhanced-depth imaging SD-OCT and CD using a linear 6 MHz to 18 MHz transducer. The maximal peak systolic velocity and resistance index (RI) were obtained for the ophthalmic artery (OA), short posterior ciliary artery (SPCA), and central retinal artery (CRA) and correlated with the subfoveal CT measured by SD-OCT.
Twenty-seven eyes of 27 healthy patients were enrolled (mean age: 40.6 ± 12.4 years; range: 27-68 years). An inverse proportional relationship (P = .0496) was identified between the RI of the SPCA (mean, 0.6117 ± 0.07911) and the subfoveal CT (319.9 µm ± 83.79 µm) but not between the RI and the OA (mean: 0.7019 µm ± 0.07317 µm) or the CRA (mean: 0.68843 µm ± 0.08994 µm).
The results of this study suggested there is an inverse proportional relationship between the RI of the SPCA and the subfoveal CT. The data also suggested a correlation between a decrease in the CT and increased RI in the retrobulbar arteries. Therefore, lower choroidal blood flow may explain the thinner CT in normal subjects.
研究正常受试者中，光谱域光学相干断层扫描（SD - OCT）测量的脉络膜厚度（CT）与彩色多普勒血流仪（CD）测量的球后血流之间的相关性。
健康受试者使用线性6兆赫兹至18兆赫兹换能器接受增强深度成像SD - OCT和CD检查。获取眼动脉（OA）、睫状后短动脉（SPCA）和视网膜中央动脉（CRA）的最大收缩期峰值速度和阻力指数（RI），并将其与SD - OCT测量的黄斑中心凹下CT进行相关性分析。
纳入27例健康患者的27只眼（平均年龄：40.6±12.4岁；范围：27 - 68岁）。发现SPCA的RI（平均值，0.6117±0.07911）与黄斑中心凹下CT（319.9µm±83.79µm）之间存在反比关系（P = 0.0496），但RI与OA（平均值：0.7019µm±0.07317µm）或CRA（平均值：0.68843µm±0.08994µm）之间不存在反比关系。
本研究结果表明，SPCA的RI与黄斑中心凹下CT之间存在反比关系。数据还表明，CT降低与球后动脉RI增加之间存在相关性。因此，脉络膜血流降低可能解释了正常受试者中CT较薄的原因。
