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癫痫与抗癫痫药物所致性欲减退——被忽视的心理社会共病情况

Epilepsy and AED-induced decreased libido - The unasked psychosocial comorbidity.

作者信息

Kaufman Kenneth R, Wong Stephen, Sivaraaman Kartik, Anim Candy, Delatte David

机构信息

Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Department of Neurology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Department of Anesthesiology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Department of Neurology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

出版信息

Epilepsy Behav. 2015 Nov;52(Pt A):236-8. doi: 10.1016/j.yebeh.2015.09.015. Epub 2015 Nov 6.

Abstract

Therapeutic treatment for persons with epilepsy (PWE) should address seizure control and the broad spectrum of associated comorbidities. Since both epilepsy and antiepileptic drugs (AEDs) can induce decreased libido, sexual health assessment is an important aspect of quality care in PWE as well as other patients receiving AEDs. This paper presents findings from a pilot quality initiative conducted in the ambulatory care epilepsy, pain management, and psychiatric services (N=15 clinicians) which addressed two themes: 1) whether libido is routinely questioned with/without the electronic medical record (EMR) and 2) clinicians' knowledge that both epilepsy and AEDs can induce decreased libido. All clinicians used the EMR, 40% used the GU-ROS section, but only 1 clinician (6.67%) questioned patients regarding libido. Of the clinicians, 26.7% demonstrated knowledge that both AEDs and epilepsy can cause decreased libido. Our results suggest that a treatment gap for epilepsy-induced and AED-induced decreased libido may be related to systems issues (duration of clinical visit, billing codes, EMR template) and physician barriers including decreased knowledge. Further research in this field and replication of this pilot quality initiative are indicated.

摘要

癫痫患者(PWE)的治疗应着眼于控制癫痫发作以及处理一系列相关的合并症。由于癫痫和抗癫痫药物(AEDs)均可导致性欲减退,因此性健康评估对于癫痫患者以及其他接受AEDs治疗的患者而言,是优质护理的一个重要方面。本文介绍了一项在门诊癫痫、疼痛管理及精神科服务中开展的试点质量改进项目(N = 15名临床医生)的研究结果,该项目涉及两个主题:1)无论有无电子病历(EMR),是否会常规询问患者性欲情况;2)临床医生对癫痫和AEDs均可导致性欲减退的认知。所有临床医生均使用EMR,40%使用泌尿生殖系统回顾(GU-ROS)板块,但仅有1名临床医生(6.67%)询问过患者的性欲情况。在这些临床医生中,26.7%了解AEDs和癫痫均可导致性欲减退。我们的研究结果表明,癫痫及AEDs所致性欲减退的治疗差距可能与系统问题(临床就诊时长、计费代码、EMR模板)以及医生方面的障碍(包括知识欠缺)有关。该领域需要进一步开展研究并重复此项试点质量改进项目。

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