Patel Hiren, Patel Charmi, Soni Mrugesh, Patel Amit, Banda Venkat
From the Baton Rouge General Medical Center, an affiliate of Tulane University School of Medicine, Baton Rouge, Louisiana (HP, CP, VB); Cardiovascular Institute of the South, Zachary, Louisiana (MS); and Cardiovascular Institute of the South, Baton Rouge, Louisiana (AP).
Medicine (Baltimore). 2015 Oct;94(41):e1709. doi: 10.1097/MD.0000000000001709.
Bacterial pericarditis is a rapidly progressive and highly fatal infection, and is often diagnosed postmortem in half of the cases. Even with drainage and antibiotics, the mortality rate is high. Gram-positive cocci, specifically Streptococcus penumoniae, have been the most common cause of bacterial pericarditis with a preceding primary site of infection. Following the introduction of antibiotics in the 1940s and more recently the pneumococcal conjugate vaccine, the incidence has drastically decreased.We describe an extremely rare case of primary streptococcus pneumoniae purulent pericarditis that presented with cardiac tamponade. The patient was successfully treated with broad-spectrum antibiotics and urgent pericardiocentesis.Due to the high mortality rate with purulent pericarditis, a high index of suspicion is needed when acute pericarditis is suspected for early diagnosis to instate appropriate therapy with antibiotics and drainage.
细菌性心包炎是一种进展迅速且致死率高的感染性疾病,半数病例常在死后才得以诊断。即便进行了引流并使用抗生素治疗,死亡率依然很高。革兰氏阳性球菌,尤其是肺炎链球菌,一直是细菌性心包炎最常见的病因,且之前存在原发性感染部位。自20世纪40年代引入抗生素以及最近引入肺炎球菌结合疫苗后,发病率已大幅下降。我们描述了一例极为罕见的原发性肺炎链球菌脓性心包炎病例,该病例表现为心脏压塞。患者通过广谱抗生素和紧急心包穿刺术成功治愈。鉴于脓性心包炎死亡率高,当怀疑急性心包炎时,需要高度怀疑以进行早期诊断,从而及时采取抗生素和引流的适当治疗措施。