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暴发性原发性链球菌性心包炎病例报告

A case report of fulminant primary streptococcal pericarditis.

作者信息

Bousoula Eleni, Stratinaki Maria, Malakos Ioannis, Sbarouni Eftihia

机构信息

Onassis Cardiac Surgery Centre, Syngrou Av. 356, Kalithea 176 74 Athens, Greece.

出版信息

Eur Heart J Case Rep. 2021 Jun 21;5(6):ytab185. doi: 10.1093/ehjcr/ytab185. eCollection 2021 Jun.

Abstract

BACKGROUND

Bacterial pericarditis is a rare, rapidly progressive, and highly fatal infection, even with drainage and antibiotics. Gram-positive cocci, specifically , have been the most common cause of bacterial pericarditis from either haematogenous dissemination, or spread from another adjacent site of infection. Following the introduction of antibiotics in the 1940s and more recently the pneumococcal conjugate vaccine, the incidence has drastically decreased.

CASE SUMMARY

A previously healthy young male was diagnosed with acute pericarditis with no signs of haemodynamic compromise on initial presentation. Several hours later, he became unstable suffering from cardiac tamponade and septic shock. Despite urgent pericardiocentesis and drainage of purulent fluid, culture positive for streptococcus pneumoniae, multi-organ failure was eventually fatal.

DISCUSSION

We describe a rare case of primary purulent pericarditis leading to tamponade, septic shock, and death. Due to the high mortality rate of purulent pericarditis, a high index of suspicion is needed in order to initiate appropriate therapy with antibiotics and drainage.

摘要

背景

细菌性心包炎是一种罕见、进展迅速且死亡率很高的感染性疾病,即便进行引流和使用抗生素治疗亦是如此。革兰氏阳性球菌,尤其是通过血行播散或从其他邻近感染部位蔓延,一直是细菌性心包炎最常见的病因。自20世纪40年代引入抗生素以及最近引入肺炎球菌结合疫苗以来,其发病率已大幅下降。

病例摘要

一名既往健康的年轻男性初诊时被诊断为急性心包炎,无血流动力学不稳定的迹象。数小时后,他病情恶化,出现心脏压塞和感染性休克。尽管紧急进行了心包穿刺并引流了脓性液体,培养结果显示肺炎链球菌阳性,但多器官功能衰竭最终导致死亡。

讨论

我们描述了一例罕见的原发性脓性心包炎病例,该病例导致了心脏压塞、感染性休克和死亡。由于脓性心包炎的死亡率很高,因此需要高度怀疑,以便启动适当的抗生素治疗和引流。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cef/8274645/8117bfbdf88b/ytab185f1.jpg

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