埃塞俄比亚吉马大学专科医院接受随访的心力衰竭患者的营养不良及相关因素
Malnutrition and associated factors among heart failure patients on follow up at Jimma university specialized hospital, Ethiopia.
作者信息
Amare Hiwot, Hamza Leja, Asefa Henok
机构信息
Department of Internal Medicine, Jimma University, Jimma, Ethiopia.
Department of Epidemiology and Biostatistics, Jimma University, Jimma, Ethiopia.
出版信息
BMC Cardiovasc Disord. 2015 Oct 15;15:128. doi: 10.1186/s12872-015-0111-4.
BACKGROUND
Malnutrition and cachexia are serious consequences of numerous chronic diseases. Severe heart failure patients could be related with marked weight loss. Malnutrition is associated with poor prognosis among heart failure patients. Despite its implication, factors associated with malnutrition among heart failure patients in Africa and Ethiopia was not addressed. Hence, in this study we tried to determine factors associated with malnutrition among heart failure patients on follow up at Jimma University specialized hospital, Ethiopia.
METHODS
A cross-sectional study was done on 284 randomly selected heart failure patients. The nutritional status of the patients was assessed based on their serum albumin level (normal value 4-5 mg/dl) and triceps skin fold thickness. The data was analyzed using SPSS version 20.0. Multivariable logistic regression was used to identify factors associated with malnutrition among heart failure patients using SPSS 20.0.
RESULTS
Based on serum albumin and triceps skin fold thickness, 77.8 % of patients were malnourished. Mean age of the patients was 48.3 ± 15.9 years. The commonest cause of heart failure was ischemic heart disease (34.9 %). Hypertension (36 %) was the commonest co morbid disease. Forty four percent of patients had New York heart association functional class II heart failure. Serum hemoglobin (AOR = 0.77, 95 % CI: 0.67-0.92) was found to be significantly associated with nutritional status of heart failure patients. As serum hemoglobin increases by 1gm/dl, the risk of malnutrition decreased by 15 % (P value = 0.03).
CONCLUSIONS
The majority of patients were malnourished. A higher hemoglobin concentration was associated with reduced odds of being malnourished.
背景
营养不良和恶病质是许多慢性疾病的严重后果。重度心力衰竭患者可能伴有显著体重减轻。营养不良与心力衰竭患者的不良预后相关。尽管存在这种关联，但非洲和埃塞俄比亚心力衰竭患者中与营养不良相关的因素尚未得到探讨。因此，在本研究中，我们试图确定埃塞俄比亚吉马大学专科医院随访的心力衰竭患者中与营养不良相关的因素。
方法
对284例随机选取的心力衰竭患者进行了横断面研究。根据患者的血清白蛋白水平（正常值4 - 5mg/dl）和肱三头肌皮褶厚度评估其营养状况。使用SPSS 20.0软件对数据进行分析。采用多变量逻辑回归分析，通过SPSS 20.0软件确定心力衰竭患者中与营养不良相关的因素。
结果
根据血清白蛋白和肱三头肌皮褶厚度，77.8%的患者存在营养不良。患者的平均年龄为48.3±15.9岁。心力衰竭最常见的病因是缺血性心脏病（34.9%）。高血压（36%）是最常见的合并症。44%的患者为纽约心脏协会心功能II级心力衰竭。血清血红蛋白（调整后比值比=0.77，95%可信区间：0.67 - 0.92）被发现与心力衰竭患者的营养状况显著相关。血清血红蛋白每增加1gm/dl，营养不良的风险降低15%（P值=0.03）。
结论
大多数患者存在营养不良。较高的血红蛋白浓度与较低的营养不良几率相关。
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