Department of Cardiology, Medical University of Lublin, Jaczewskiego 8, 20-093 Lublin, Poland.
Department of Experimental Immunology, Medical University of Lublin, 20-093 Lublin, Poland.
Nutrients. 2023 Jul 24;15(14):3264. doi: 10.3390/nu15143264.
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, far ahead of cancer. Epidemiological data emphasize the participation of many risk factors that increase the incidence of CVDs, including genetic factors, age, and sex, but also lifestyle, mainly nutritional irregularities and, connected with them, overweight and obesity, as well as metabolic diseases. Despite the importance of cardiovascular problems in the whole society, the principles of prevention of CVDs are not widely disseminated, especially among the youngest. As a result, nutritional neglect, growing from childhood and adolescence, translates into the occurrence of numerous disease entities, including CVDs, in adult life. This review aimed to draw attention to the role of selected minerals and vitamins in health and the development and progression of CVDs in adults and children. Particular attention was paid to the effects of deficiency and toxicity of the analyzed compounds in the context of the cardiovascular system and to the role of intestinal microorganisms, which by interacting with nutrients, may contribute to the development of cardiovascular disorders. We hope this article will draw the attention of society and the medical community to emphasize promoting healthy eating and proper eating habits in children and adults, translating into increased awareness and a reduced risk of CVD.
心血管疾病(CVDs)是全球范围内的主要死亡原因,远远超过癌症。流行病学数据强调了许多增加 CVDs 发病率的风险因素的参与,包括遗传因素、年龄和性别,但也包括生活方式,主要是营养不规律,以及与之相关的超重和肥胖,以及代谢疾病。尽管心血管问题在整个社会中都很重要,但 CVDs 的预防原则并没有得到广泛传播,尤其是在最年轻的人群中。因此,从儿童和青少年时期开始的营养忽视,转化为成年后发生许多疾病实体,包括 CVDs。本综述旨在引起人们对某些矿物质和维生素在健康以及成年人和儿童 CVD 发生和发展中的作用的关注。特别关注了分析化合物在心血管系统中缺乏和毒性的影响,并关注了肠道微生物的作用,这些微生物通过与营养物质相互作用,可能导致心血管疾病的发生。我们希望本文能引起社会和医学界的关注,强调在儿童和成人中促进健康饮食和良好的饮食习惯,从而提高认识并降低 CVD 的风险。