Dyasanoor Sujatha, Abdul Khader Nishat Fatima
Department of Oral Medicine and Maxillofacial Radiology, The Oxford Dental College and Research Hospital, Bengaluru, Karnataka, India.
Contemp Clin Dent. 2016 Apr-Jun;7(2):146-52. doi: 10.4103/0976-237X.183042.
To assess and compare the salivary flow rate (SFR), pH and taste perception among oral submucous fibrosis (OSMF) and apparently healthy subjects.
Ninety subjects (45 OSMF + 45 controls) were enrolled in the study for estimating and analogizing the SFR, pH, and taste perception executing modified Schirmer, pH, and taste strips. The SFR, pH, and taste perception were evaluated and compared between 14 Stage I and 31 Stage II OSMF subjects. The entered data were analyzed using SPSS 21.0 software.
A statistically significant decrease in SFR among OSMF group (23.4 mm at 3(rd) min) and hypogeusia to salty (62.2%), and dysgeusia to sour taste (40%) when compared to apparently healthy subjects (30.7 mm at 3(rd) min) was noted. Statistical significance (P < 0.05%) inferring hyposalivation in Stage II OSMF (24.1 mm at 3(rd) min) juxtaposing with Stage I OSMF (31.4 mm at 3(rd) min). Statistically significant hypogeusia to salty (n = 23) and sweet (n = 16) and dysgeusia (n = 14) to sour among Stage II OSMF when differentiated with Stage I OSMF. The mean pH among the OSMF and control groups demonstrated no statistical significance.
The findings from the study demonstrated marked decrease of SFR and taste perception to salty and sour among Stage II OSMF when compared to Stage I OSMF subjects.
评估和比较口腔黏膜下纤维化(OSMF)患者与表面健康受试者的唾液流速(SFR)、pH值和味觉感知。
90名受试者(45名OSMF患者 + 45名对照)参与本研究,采用改良的Schirmer试验、pH试纸和味觉试纸评估并比较SFR、pH值和味觉感知。对14名I期和31名II期OSMF受试者的SFR、pH值和味觉感知进行评估和比较。使用SPSS 21.0软件对录入的数据进行分析。
与表面健康受试者(第3分钟时为30.7毫米)相比,OSMF组的SFR显著降低(第3分钟时为23.4毫米),对咸味的味觉减退(62.2%),对酸味的味觉异常(40%)。具有统计学意义(P < 0.05%),表明II期OSMF(第3分钟时为24.1毫米)与I期OSMF(第3分钟时为31.4毫米)相比存在唾液分泌减少。与I期OSMF相比,II期OSMF对咸味(n = 23)和甜味(n = 16)的味觉减退以及对酸味的味觉异常(n = 14)具有统计学意义。OSMF组和对照组之间的平均pH值无统计学意义。
研究结果表明,与I期OSMF受试者相比,II期OSMF患者的SFR以及对咸味和酸味的味觉感知显著降低。