Ma Jiehua, Kan Yanjing, Zhang Aixia, Lei Yu, Yang Bin, Li Ping, Pan Lianjun
State Key Laboratory of Reproductive Medicine, Department of Reproductive Health, Nanjing Maternity and Child Health Care Hospital affiliated with Nanjing Medical University, Nanjing, Jiangsu, China.
State Key Laboratory of Reproductive Medicine, Department of Cervical Care, Nanjing Maternity and Child Health Care Hospital affiliated with Nanjing Medical University, Nanjing, Jiangsu, China.
PLoS One. 2015 Oct 16;10(10):e0141004. doi: 10.1371/journal.pone.0141004. eCollection 2015.
Non-malignant cervical diseases are common causes of disease among women worldwide. Although many studies have focused on sexual function in women with cervical cancer, little is known about the prevalence of female sexual dysfunction and its risk factors in women with non-malignant cervical diseases. The present study aims to assess sexual function in Chinese women with non-malignant cervical diseases and to identify potential risk factors for these diseases. A cross-sectional hospital-based survey was conducted in Nanjing, China. The Chinese version of the Female Sexual Function Index (CVFSFI) was used to evaluate sexual function. Three hundred three women who had been diagnosed with at least one non-malignant cervical disease and 293 healthy women were recruited from Nanjing Maternity and Child Health Hospital of Nanjing Medical University. We found that women with non-malignant cervical diseases had a significantly higher prevalence of female sexual dysfunction (FSD) (51.8% vs. 34.8%), low desire (43.2% vs. 26.3%), arousal disorder (41.6% vs. 28.3%), and lubrication disorder (51.2% vs. 36.9%) compared with the control group. Cervicitis and cervical intraepithelial neoplasia (CIN) were found to be independent risk factors for FSD. Our study indicates that women with cervicitis and CIN are at a high risk for FSD and deserve focused initial and follow-up management.
非恶性宫颈疾病是全球女性常见的疾病原因。尽管许多研究关注宫颈癌女性的性功能,但对于非恶性宫颈疾病女性中女性性功能障碍的患病率及其危险因素知之甚少。本研究旨在评估患有非恶性宫颈疾病的中国女性的性功能,并确定这些疾病的潜在危险因素。在中国南京进行了一项基于医院的横断面调查。使用中文版女性性功能指数(CVFSFI)来评估性功能。从南京医科大学附属南京妇幼保健院招募了303名被诊断患有至少一种非恶性宫颈疾病的女性和293名健康女性。我们发现,与对照组相比,患有非恶性宫颈疾病的女性中女性性功能障碍(FSD)的患病率显著更高(51.8%对34.8%),性欲低下(43.2%对26.3%)、性唤起障碍(41.6%对28.3%)和润滑障碍(51.2%对36.9%)。宫颈炎和宫颈上皮内瘤变(CIN)被发现是FSD的独立危险因素。我们的研究表明,患有宫颈炎和CIN的女性患FSD的风险很高,值得进行重点的初始和随访管理。