Gong Haiying, Pa Lize, Wang Ke, Mu Hebuli, Dong Fen, Ya Shengjiang, Xu Guodong, Tao Ning, Pan Li, Wang Bin, Shan Guangliang
Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China.
Xinjiang Uyghur Autonomous Region Centre for Disease Control and Prevention, Urumqi 830001, China.
Int J Environ Res Public Health. 2015 Oct 14;12(10):12792-802. doi: 10.3390/ijerph121012792.
To estimate the prevalence of diabetes and identify risk factors in the Uyghur and Han population in Xinjiang, China.
A cross-sectional study in urban and rural areas in Xinjiang, including 2863 members of the Uyghur population and 3060 of the Han population aged 20 to 80 years, was conducted from June 2013 to August 2013. Data on fasting plasma glucose (FPG) and personal history of diabetes were used to estimate the prevalence of diabetes. Data on demographic characteristics, lifestyle risk factors, and lipid profiles were collected to identify risks factors using the multivariate logistic regression model.
In urban areas, the age- and gender-standardized prevalence of diabetes was 8.21%, and the age- and gender-standardized prevalence of diabetes was higher in the Uyghur population (10.47%) than in the Han population (7.36%). In rural areas, the age- and gender-standardized prevalence of diabetes was 6.08%, and it did not differ significantly between the Uyghur population (5.71%) and the Han population (6.59%). The results of the multivariate logistic regression analysis showed that older age, obesity, high triglycerides (TG), and hypertension were all associated with an increased risk of diabetes in the Uyghur and Han population. Urban residence and low high-density lipoprotein cholesterol (HDL-C) were associated with an increased risk of diabetes in the Uyghur population. Being an ex-drinker was associated with an increased risk of diabetes and heavy physical activity was associated with a decreased risk of diabetes in the Han population.
Our study indicates that diabetes is more prevalent in the Uyghur population compared with the Han population in urban areas. Strategies aimed at the prevention of diabetes require ethnic targeting.
评估中国新疆维吾尔族和汉族人群中糖尿病的患病率并确定危险因素。
2013年6月至2013年8月在新疆城乡地区开展了一项横断面研究,纳入了2863名年龄在20至80岁的维吾尔族人群成员和3060名汉族人群成员。利用空腹血糖(FPG)数据和糖尿病个人史来评估糖尿病患病率。收集人口统计学特征、生活方式危险因素和血脂谱数据,使用多变量逻辑回归模型确定危险因素。
在城市地区,年龄和性别标准化的糖尿病患病率为8.21%,维吾尔族人群(10.47%)的年龄和性别标准化糖尿病患病率高于汉族人群(7.36%)。在农村地区,年龄和性别标准化的糖尿病患病率为6.08%,维吾尔族人群(5.71%)和汉族人群(6.59%)之间无显著差异。多变量逻辑回归分析结果显示,年龄较大、肥胖、高甘油三酯(TG)和高血压均与维吾尔族和汉族人群患糖尿病风险增加相关。城市居住和低高密度脂蛋白胆固醇(HDL-C)与维吾尔族人群患糖尿病风险增加相关。在汉族人群中,既往饮酒者患糖尿病风险增加,而剧烈体力活动与患糖尿病风险降低相关。
我们的研究表明,在城市地区,维吾尔族人群中糖尿病比汉族人群更普遍。预防糖尿病的策略需要针对不同民族。